Bismuth(III) triflate: An Efficient Catalyst for the Synthesis of Diverse Biologically Relevant Heterocycles

Abstract

Last decade has seen a tremendous applications of bismuth(III) trifluoromethanesulfonate [Bi(OTf)3] as an efficient, cheap, environmentally benign, Lewis acidic catalyst for the various organic transformations. On the other hand heterocycles are very common in naturally occurring compounds and are the privileged structural subunit of many marketed drug molecules. The present review summarizes the applications of bismuth(III) triflate as a catalyst for the synthesis of diverse biologically relevant heterocycles reported so far.

Magnetically Separable Transition Metal Ferrites: Versatile Heterogeneous Nano‐Catalysts for the Synthesis of Diverse Bioactive Heterocycles

“…Das et al [64] ( (32,33) under the same optimized conditions. The magnetic catalyst was recovered quantitatively and recycled six times without any loss in its activity.…”

“…In continuation of our strong interest in reviewing the various approaches for the synthesis of diverse heterocyclic systems, [25][26][27][28][29][30][31][32][33] this review summarizes, the application of nano metal ferrites as an efficient, heterogeneous, magnetic catalyst for the synthesis of biologically promising heterocyclic scaffolds.…”

One‐Pot Pseudo Five Component Synthesis of Biologically Relevant 1,2,6‐Triaryl‐4‐arylamino‐piperidine‐3‐ene‐3‐ carboxylates: A Decade Update

“…In continuation of our interest in reviewing the various approaches for the synthesis of diverse heterocyclic systems, this review summarizes the one‐pot pseudo five‐component synthesis of 1,2,6‐triaryl‐4‐arylamino‐piperidine‐3‐ene‐3‐carboxylates under various reaction conditions reported so far.…”

“…Plausible mechanism for this one-pot pseudo fivecomponent reaction is shown in Scheme 2. In continuation of our interest in reviewing the various approaches for the synthesis of diverse heterocyclic systems, [33][34][35][36][37][38] this review summarizes the one-pot pseudo fivecomponent synthesis of 1,2,6-triaryl-4-arylamino-piperidine-3ene-3-carboxylates under various reaction conditions reported so far. [39] first reported the synthesis of functionalized piperidines from one-pot pseudo five component reactions of substituted benzaldehydes, anilines and methyl acetoacetate using a catalytic amount of indium(III) chloride as catalyst in acetonitrile at room temperature.…”

Recent developments on nano-ZnO catalyzed synthesis of bioactive heterocycles

“…Heterocyclic moieties are very common in naturally occurring compounds and are important because of their significant biological efficacies that include anticancer [3], cytotoxic [4], anti-malarial [5], anti-microbial [6], anti-inflammatory [7], anti-oxidant 1 3 [8] and many more [9,10]. Figure 1 represents a glimpse of marketed drugs containing heterocycles as the core structural unit [11][12][13][14][15][16].…”