BisGMA analogues as monomers and diluents for dental restorative composite materials

Srivastava, Rohit; Liu, Jianhong; He, Chuanxin; Sun, Yuyu

doi:10.1016/j.msec.2018.01.011

Cited by 33 publications

(24 citation statements)

References 25 publications

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“…It is well known that the mechanical properties of the dental composite should be studied apart from clinical testing . In this regard, it is reported that resin chemistry, filler technology (filler shape, size, and content) and coupling phenomena affect the mechanical properties of dental composite .…”

Section: Resultsmentioning

confidence: 99%

Mechanical and thermo‐mechanical characterization of glass ionomer‐filled dental composite

et al. 2018

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In this study, the effect of adding glass ionomer (GI) Restorative Cement (0−30 wt%) on the mechanical and thermo‐mechanical characterization of dental composite has been discussed. The characterization of dental composites was done by performing Fourier transform infrared spectroscopy, hardness test, compression test, flexural strength test, dynamic mechanical analysis (DMA), thermo gravimetric analysis (TGA). The finding of experiments indicated that the addition of 10 wt% of GI increased the water hardness, flexural strength and compressive strength by 88.48, 15.95, and 17.74%, respectively. DMA results revealed that the storage modulus was initially increased by 88% when GI was increased up to 20 wt%, however, further increase of GI up to 30 wt% resulted in decrease in the storage modulus by 16.4%. Also, loss modulus was increased by 41.6% when GI was increased by 10 wt%, however, it was further decreased by 2.94% and by 35.29% on addition of GI filler content up to 20 and 30 wt%, respectively. Incorporation of GI up to 10 wt% decreased the damping factor by 36.36% but further addition of GI up to 20 and 30 wt% increased the damping factor of dental composite by 14.2 and 50%. TGA indicated that thermal degradation temperature was increased with the addition of GI filler. POLYM. COMPOS., 40:3361–3367, 2019. © 2018 Society of Plastics Engineers

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Section: Resultsmentioning

confidence: 99%

Mechanical and thermo‐mechanical characterization of glass ionomer‐filled dental composite

et al. 2018

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“…The features of BisGMA contain high molecular weight and viscosity, low volatility, fast polymerization by organic light. 26 There is sufficient evidence to prove that BisGMA monomers dissociate from the polymer composite restorative materials after treatment with water-or organic-based solvents for 1-180 days. 9,10 Cytotoxicity could be induced by BisGMA in macrophages, dental pulp cells, and gingival fibroblasts, which can lead to oral inflammation.…”

Section: Effects Of Rutin On Bisgma-inhibited Aoe Activities In Rawmentioning

confidence: 99%

Rutin‐protected BisGMA‐induced cytotoxicity, genotoxicity, and apoptosis in macrophages through the reduction of the mitochondrial apoptotic pathway and induction of antioxidant enzymes

Huang

Chang

et al. 2020

Environmental Toxicology

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Bisphenol-A-glycidyldimethacrylate (BisGMA) is a resin monomer frequently used in dentin restorative treatments. The leakage of BisGMA monomer from BisGMA-based polymeric resins can lead to cytotoxicity in macrophages. Rutin has various beneficial bioeffects, including antioxidation and antiinflammation. In this study, we found that pretreatment of RAW264.7 macrophages with rutin-inhibited cytotoxicity induced by BisGMA in a concentration-dependent manner. BisGMA-induced apoptosis, which was detected by levels of phosphatidylserine from the internal to the external membrane and formation of sub-G1, and genotoxicity, which was detected by cytokinesis-blocked micronucleus and single-cell gel electrophoresis assays, were inhibited by rutin in a concentration-dependent manner. Rutin suppressed the BisGMA-induced activation of caspase-3 and-9 rather than caspase-8. Rutin inhibited the activation of the mitochondrial apoptotic pathway, including cytochrome C release and mitochondria disruption, after macrophages were treated with Yin-Che Lu and Yu-Hsiang Kuan contributed equally to this work.

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“…With the development of dental composites, many studies have confirmed that the compositions of dental composites and the matrix/filler interfacial interaction have a great influence on their service performance . In addition to the well‐studied compositions of the resin matrix and fillers, some previous work also found that the excellent interfacial compatibility and strong interfacial interaction of the organic/inorganic phase are beneficial for the long‐term clinical application of dental composites .…”

Section: Modification Technologies To Improve the Matrix/filler Intermentioning

confidence: 99%

Dental Restorative Resin Composites: Modification Technologies for the Matrix/Filler Interface

Chen

Wang

et al. 2018

Macro Materials & Eng

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Dental restorative resin composites are a pivotal class of organic/inorganic hybrid materials. The main reasons for their failure are secondary caries and dental composite fractures, which prevent their long‐term service in posterior restorations. A remedy to these problems is improving the interfacial adhesion between the resin matrix and the fillers. Surface‐modified inorganic fillers show strong potential as more than just a bond between these two phases and can therefore be considered a medium to compensate for the deficits of dental composites. This paper mainly discusses strategies to improve the interfacial adhesion of dental composites, including surface treatments of fillers with coupling agents, polymers, and tetraethyl orthosilicate (TEOS) coatings, as well as the selection of porous fillers capable of micromechanical resin matrix/filler interlocking. Additionally, the existing deficiencies of these strategies and the prospects for dental composites are discussed.

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BisGMA analogues as monomers and diluents for dental restorative composite materials

Cited by 33 publications

References 25 publications

Mechanical and thermo‐mechanical characterization of glass ionomer‐filled dental composite

Mechanical and thermo‐mechanical characterization of glass ionomer‐filled dental composite

Rutin‐protected BisGMA‐induced cytotoxicity, genotoxicity, and apoptosis in macrophages through the reduction of the mitochondrial apoptotic pathway and induction of antioxidant enzymes

Dental Restorative Resin Composites: Modification Technologies for the Matrix/Filler Interface

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