Biosynthesis of silver nanoparticles: Elucidation of prospective mechanism and therapeutic potential

Mittal, Amit Kumar; Bhaumik, Jayeeta; Kumar, Sanjay; Banerjee, Uttam Chand

doi:10.1016/j.jcis.2013.10.018

Cited by 288 publications

(160 citation statements)

References 42 publications

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“…39 Similarly, the WPE-mediated AgNPs also showed four characteristic peaks at 38.13°, 44.23°, 64.53°, and 77.39° attributed to 111, 200, 220, and 311 crystalline planes of FCC crystalline structure of metallic silver ( Figure 8B). 3 Some unidentified crystalline peaks were also observed at 32.33°, 46.37°, and 68.93°, which are also apparent in many other works in which the XRD pattern includes the relevant 2θ range. 44 These peaks might be due to the presence of bioactive compounds on the surface of AgNPs, which are responsible for their capping.…”

Section: Xrd Analysis Of Agnpssupporting

confidence: 61%

“…3,4,6,37,38 Since the WPE-and TDZ-induced CE of L. usitatissimum contain high levels of polyphenols and flavonoids, we expect that they will serve as reducing and capping agents for the biosynthesis of AgNPs. Therefore, we synthesized AgNPs using WPE-and TDZ-induced CE to find out the better reducing source.…”

Section: Wpe-and Ce-mediated Biosynthesis Of Agnpsmentioning

confidence: 99%

“…The absorption peaks in the region of 3,774.38-3,601.23 cm -1 were assigned to strong -OH stretching in alcohols, flavonoids, and phenolic compounds. 3 The intense bands in the region of 2,934.07-2,891.01 cm -1 correspond to O-H stretching …”

Section: Effect Of Reaction Time On Synthesis and Stability Of Agnpsmentioning

confidence: 99%

“…However, these synthetic methods, involving different chemicals, are expensive and may lead to the presence of noxious chemical species tangled on the surface of nanoparticles, which may have adverse effects in various biological and biomedical applications. 2,3 This increases the growing need to develop environment-friendly procedures for synthesis of metallic nanoparticles through 716 anjum and abbasi "green synthesis" and other new biological approaches. 4 Synthesis of metallic nanoparticles by plant extracts is the most implemented method of green, eco-friendly fabrication of nanoparticles and also has a distinctive advantage that plants are extensively distributed, easily accessible, less biohazardous, and act as a source of numerous metabolites.…”

Section: Introductionmentioning

confidence: 99%

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Thidiazuron-enhanced biosynthesis and antimicrobial efficacy of silver nanoparticles via improving phytochemical reducing potential in callus culture of Linum usitatissimum L.

Anjum¹,

Abbasi²

2016

IJN

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Green synthesis of silver nanoparticles (AgNPs) by using plants is an emerging class of nanobiotechnology. It revolutionizes all domains of medical sciences by synthesizing chemical-free AgNPs for various biomedical applications. In this report, AgNPs were successfully synthesized by using whole plant extract (WPE) and thidiazuron-induced callus extract (CE) of Linum usitatissimum . The phytochemical analysis revealed that the total phenolic and flavonoid contents were higher in CE than that in WPE. Ultraviolet-visible spectroscopy of synthesized AgNPs showed a characteristic surface plasmon band in the range of 410–426 nm. Bioreduction of CE-mediated AgNPs was completed in a shorter time than that of WPE-mediated AgNPs. Scanning electron microscopy showed that both types of synthesized AgNPs were spherical in shape, but CE-mediated AgNPs were smaller in size (19–24 nm) and more scattered in distribution than that of WPE-mediated AgNPs (49–54 nm). X-ray diffraction analysis confirmed crystalline nature (face-centered cubic) of both types of AgNPs. Fourier-transform infrared spectroscopy revealed that the polyphenols and flavonoids were mainly responsible for reduction and capping of synthesized AgNPs. Energy dispersive X-ray analysis further confirmed the successful synthesis of AgNPs. Moreover, the synthesized AgNPs were found to be stable over months with no change in the surface plasmon bands. More importantly, CE-mediated AgNPs displayed significantly higher bactericidal activity against multiple drug-resistant human pathogens than WPE-mediated AgNPs. The present work highlighted the potent role of thidiazuron in in vitro-derived cultures for enhanced biosynthesis of chemical-free AgNPs, which can be used as nanomedicines in many biomedical applications.

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Section: Xrd Analysis Of Agnpssupporting

confidence: 61%

Section: Wpe-and Ce-mediated Biosynthesis Of Agnpsmentioning

confidence: 99%

Section: Effect Of Reaction Time On Synthesis and Stability Of Agnpsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Thidiazuron-enhanced biosynthesis and antimicrobial efficacy of silver nanoparticles via improving phytochemical reducing potential in callus culture of Linum usitatissimum L.

Anjum¹,

Abbasi²

2016

IJN

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“…The color of the colloidal solution of AgNPs depends on the size and shape of the nanoparticles. Usually, metal nanoparticles were analyzed in the range from 300 to 800 nm wavelength, and formation of AgNPs can be detected commonly from the absorption measurement in the wavelength ranges of 400-450 nm [34]. In this present study, the absorption band was observed from 430 to 456 nm for different incubation time (Fig.…”

Section: Uv-visible Spectroscopysupporting

confidence: 50%

Psidium Guajava: A Novel Plant in the Synthesis of Silver Nanoparticles for Biomedical Applications.

Sharmila¹,

Ranjith²,

B³

2018

Asian J Pharm Clin Res

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Objective: Synthesis of silver nanoparticles (AgNPs) using a simple, cost-effective and environmentally friendly green route approach and to study the antibacterial activity of AgNPs against human pathogens. Methods:Green route approach is used to synthesize AgNPs using Psidium guajava leaf extract. Fourier transform infrared (FTIR) was used to identify the presence of the functional group. X-ray diffraction (XRD) was used to analyze the structure of prepared AgNPs. Energy dispersive X-ray was used to the characteristic to the composition of the prepared nanoparticles. Size and morphology of the prepared AgNPs were investigated using field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM) analysis. Antibacterials efficiency of prepared AgNPs was tested against Escherichia coli and Staphylococcus aureus by well diffusion methods.Results: FTIR study shows the presence of different functional groups present in the leaves mediated AgNPs. The XRD studies yield diffraction peaks corresponding to face-centered cubic structure of Ag crystals. Spherical shaped AgNPs with a particle size of about ~55 nm were evidenced using FESEM and TEM analysis. Energy dispersive spectrum of the synthesized AgNPs confirms the presence of silver in the prepared nanoparticles. From UV-VIS analysis it is shown that the absorption band was red-shifted from 430 nm to 456 nm. The prepared AgNPs shows good antibacterial activity against E. coli and S. aureus.Conclusions: P. guajava leaf extract is a potential reducing agent to synthesize AgNPs. The green synthesis approach provides cost-effective and ecofriendly nanoparticles, which could be used in biomedical applications.

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Eco‐Friendly Noble Metal Nanoparticles for Therapeutic Applications: Present and Future Scenario

Choudhary

Madhuri

2018

Green Metal Nanoparticles

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Biosynthesis of silver nanoparticles: Elucidation of prospective mechanism and therapeutic potential

Cited by 288 publications

References 42 publications

Thidiazuron-enhanced biosynthesis and antimicrobial efficacy of silver nanoparticles via improving phytochemical reducing potential in callus culture of Linum usitatissimum L.

Thidiazuron-enhanced biosynthesis and antimicrobial efficacy of silver nanoparticles via improving phytochemical reducing potential in callus culture of Linum usitatissimum L.

Psidium Guajava: A Novel Plant in the Synthesis of Silver Nanoparticles for Biomedical Applications.

Eco‐Friendly Noble Metal Nanoparticles for Therapeutic Applications: Present and Future Scenario

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