Biosynthesis of Silver Nanoparticles by Polysaccharide of <i>Leucaena leucocephala</i> Seeds and Their Anticancer, Antifungal Properties and as Preservative of Composite Milk Sample

Taher, Mohamed A.; Khojah, Ebtihal; Darwish, Mohamed Samir; Elsherbiny, Elsherbiny A.; El-Awady, Asmaa A.; Dawood, Dawood H.

doi:10.1155/2022/7490221

Cited by 19 publications

(10 citation statements)

References 78 publications

(95 reference statements)

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“…The antifungal potential of CS/PVA, CS/PVA/INA 0.5 mM, and CS/PVA/INA 1.0 mM composites against Alternaria alternata AUMC 10301 and Botrytis cinerea AUMC 6095 (AUMC, Assiut University Mycological Centre, Asyut, Egypt) was assessed in vitro according to the method of Taher et al [ 17 ]. The tested concentration of CS or PVA in the medium was 2 g/L.…”

Section: Methodsmentioning

confidence: 99%

Impact of Isonicotinic Acid Blending in Chitosan/Polyvinyl Alcohol on Ripening-Dependent Changes of Green Stage Tomato

Taher

Elsherbiny

2023

Polymers

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The effect of isonicotinic acid (INA) in a chitosan (CS)/polyvinyl alcohol (PVA) blend on ripening-dependent changes of preserved green tomatoes (Solanum lycopersicum L.) was examined at room temperature. The results showed that CS/PVA/INA 0.5 mM and CS/PVA/INA 1.0 mM formulations retarded firmness loss and delayed the pigmentation parameters i.e., lycopene (LYP), total carotenes (TCs), and titratable acidity (TA). The CS/PVA/INA 0.5 mM and CS/PVA/INA 1.0 mM formulations were able to delay the increase in malondialdehyde (MDA) and total polyphenol (TP) contents. Furthermore, the peroxidase (POD), polyphenoloxidase (PPO), and phenylalanine ammonia-lyase (PAL) activities of tomatoes coated with CS/PVA/INA 0.5 mM and CS/PVA/INA 1.0 mM formulations were lower than those in other treatments. Meanwhile, the CS/PVA blend had the highest TP content, as well as the highest PPO and PAL activities, at the late stage of maturation. The UV analysis showed that the CS/PVA/INA blend film is a promising UV-protective food packaging material. The pure CS, PVA, and INA formulations, as well as the CS/PVA, CS/PVA/INA 0.5 mM, and CS/PVA/INA 1.0 mM formulations, were characterized by infrared (FTIR). The three polymer formulations showed strong antifungal activity against Alternaria alternata and Botrytis cinerea.

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Section: Methodsmentioning

confidence: 99%

Impact of Isonicotinic Acid Blending in Chitosan/Polyvinyl Alcohol on Ripening-Dependent Changes of Green Stage Tomato

Taher

Elsherbiny

2023

Polymers

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“…Studies indicate that these polysaccharides function as stabilizing and reducing agents, binding to metallic nanoparticles through noncovalent bonding. [ 145 ] The abundance of carboxyl and hydroxyl groups within these polysaccharides significantly contributes to enhancing solubility and stability. This quality allows for their integration into biopolymeric blends, forming a stable suspension with a negative electrostatic surface charge.…”

Section: Biopolymers Based Aerogels In Anticancer Drug Delivery Appli...mentioning

confidence: 99%

Revolutionizing Cancer Treatment: Biopolymer‐Based Aerogels as Smart Platforms for Targeted Drug Delivery

Alkhalidi,

Alahmadi,

Rizg

et al. 2024

Macromol. Rapid Commun.

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Cancer stands as a leading cause of global mortality, with chemotherapy being a pivotal treatment approach, either alone or in conjunction with other therapies. The primary goal these therapies is to inhibit the growth of cancer cells specifically, while minimizing harm to healthy dividing cells. Conventional treatments have been hampered by their side effects, often causing severe discomfort to patients. Researchers have been exploring innovative approaches to target cancer cells selectively. In this context, biopolymer‐based aerogels emerge as innovative platforms, showcasing unique properties that respond intelligently to diverse stimuli, including temperature, pH variations, magnetic fields, and redox potential. This responsiveness enables precise control over the release of anticancer drugs, enhancing therapeutic outcomes. The significance of these aerogels lies in their ability to offer targeted drug delivery with increased efficacy, biocompatibility, and a high drug payload. In this comprehensive review, we discuss the role of biopolymer‐based aerogels as an emerging functionalized platforms in anticancer drug delivery. The review addresses the unique properties of biopolymer‐based aerogels showing their smart behavior in responding to different stimuli including temperature, pH, magnetic and redox potential to control anticancer drug release. Finally, the review discusses the application of different biopolymer‐based aerogel in delivering different anticancer drugs and also discusses the potential of these platforms in gene delivery applications. This article is protected by copyright. All rights reserved

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“…An aliquot of the solution was analyzed using UV-visible spectrophotometry to track the development of silver nitrate bioreduction. Figures 2 and 3 distinctive display peaks measured at 424 nm for the methanolic extract and 442 nm for the aqueous extract [34,35], respectively. kilimandscharicum methanolic leaves extract, corresponding to a sharp peak (Figure 4).…”

Section: Uv-visible Spectroscopymentioning

confidence: 99%

Silver nanoparticle biosynthesis utilizingOcimum kilimandscharicumleaf extract and assessment of its antibacterial activity against certain chosen bacteria

Ouandaogo,

Diallo,

Odari

et al. 2023

Preprint

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Using plants in the biological production of silver nanoparticles (AgNPs) is becoming increasingly important as a practical and environmentally benign method. In the current work, silver nanoparticles were made utilizing the significantOcimum kilimandscharicum, and their potential to combat certain bacteria was discussed. Both aqueous and methanol plant extracts were used for reducing silver nitrate at different time intervals (30 to 150 minutes) and pH (2 to 11). The UV-visible absorption spectrum recorded for both methanol and aqueous extracts revealed successful synthesis of AgNPs. The antimicrobial activity of the AgNPs was evaluated againstEscherichia coliATCC 25922,Salmonella choleraesuiusATCC 10708, andStaphylococcus aureusATCC 25923. 50mg/ml was the concentration of the extracts tested. The best zone of inhibition was recorded for the methanol and aqueous-mediated AgNPs, ranging from 12±1 to 16±1mm. The methanol and aqueous extract silver nanoparticles had the same Minimum Inhibitory Concentration (6.25±0.00 mg/ml), whereas the Minimum Bactericidal Concentrations were 12.5±0.00 and 25±0.00 mg/ml, respectively. The highest inhibition zone of 16±1 mm was observed againstSalmonella choleraesuiuswith 50±0.00 mg/ml aqueous silver nanoparticles. The results show that the silver nanoparticles made withOcimum kilimandscharicumhave potent antibacterial action against those microorganisms.

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Biosynthesis of Silver Nanoparticles by Polysaccharide of Leucaena leucocephala Seeds and Their Anticancer, Antifungal Properties and as Preservative of Composite Milk Sample

Cited by 19 publications

References 78 publications

Impact of Isonicotinic Acid Blending in Chitosan/Polyvinyl Alcohol on Ripening-Dependent Changes of Green Stage Tomato

Impact of Isonicotinic Acid Blending in Chitosan/Polyvinyl Alcohol on Ripening-Dependent Changes of Green Stage Tomato

Revolutionizing Cancer Treatment: Biopolymer‐Based Aerogels as Smart Platforms for Targeted Drug Delivery

Silver nanoparticle biosynthesis utilizingOcimum kilimandscharicumleaf extract and assessment of its antibacterial activity against certain chosen bacteria

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