Biosynthesis of Gold Nanoparticles using Scytosiphon lomentaria (Brown algae) and Spyridia filamentosa (Red algae) from Kyrenia Region and Evaluation of their Antimicrobial and Antioxidant Activity

Kavaz, Doğa; Umar, Huzaifa; Zimuto, Tariro

doi:10.15671/hjbc.518593

Cited by 12 publications

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References 44 publications

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“…Some leaves and stem bark extracts used in the synthesis of ZnO NPs include Costus pictus D. Don [9], Parthenium hysterophorus L. [10], and A. lebbeck [11]. Studies report bio-extract-mediated ZnO nanoparticles with exclusive properties revealed novel alternatives to cancer therapy, anti-diabetic, antioxidant, and anti-microbial activity [12,13].…”

Section: Introductionmentioning

confidence: 99%

Biosynthesized ZnO Nanoparticles Using Albizia lebbeck Extract Induced Biochemical and Morphological Alterations in Wistar Rats

et al. 2021

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Nano-based particles synthesized via green routes have a particular structure that is useful in biomedical applications as they provide cheap, eco-friendly, and non-toxic nanoparticles. In the present study, we reported the effect of various concentrations of Zinc oxide nanoparticles synthesized using A. lebbeck stem bark extract (ZnO NPsAL) as stabilizing agent on rat biochemical profiles and tissue morphology. Adult Wistar rats weighing 170 ± 5 g were randomly classified into eight groups of five rats each; Group A served as a control fed with normal diet and water. Groups B1, B2, C1, C2, D1, D2, and E were treated with 40 mg/kg and 80 mg/kg of the 0.01, 0.05, and 0.1 M biosynthesized ZnO NPsAL and zinc nitrate daily by the gavage method, respectively. The rats were anesthetized 24 h after the last treatment, blood samples, kidney, heart, and liver tissues were collected for biochemical and histopathological analysis. The rats mean body weight, serum alkaline phosphatase, alanine aminotransferase, creatinine, urea, bilirubin, protein, albumin, globulin, total cholesterol, triacylglycerol, and high-density lipoprotein were significantly altered with an increased concentration of biosynthesized ZnO NPsAL when compared with the control group (p < 0.05; n ≥ 5). Furthermore, histopathological analysis of treated rats’ kidney, heart, and liver tissue revealed vascular congestion, tubular necrosis, inflammation, and cytoplasmic vacuolation. Biosynthesized ZnO NPsAL showed significant alteration in biochemical parameters and tissue morphology in rats with increasing concentrations of the nanoparticles.

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