Biosorption of cadmium by potential probiotic Pediococcus pentosaceus using in vitro digestion model

Abstract

An exponential increase of heavy metal toxicant in the human body is a growing health-related problem. In the present study, Pediococcus pentosaceus FB145 and FB181 strains were isolated from fermented seafood and served as highly Cd-resistant strains. The unchanged structural cells of P. pentosaceus strains after treatment with Cd cations were investigated using a scanning electron microscope energy dispersive X-ray analysis. Furthermore, both P. pentosaceus strains showed strong human gastrointestinal tract resistance properties. The Cd biosorption results fit the pseudo-second-order kinetics with capacities for P. pentosaceus FB145 and FB181 for Cd were 52.8 and 50.3 mg/g, respectively, whereas the maximum biosorption capacities were 52.65 and 50.35 mg/g, respectively. The equilibrium data were well fitted to the Freundlich isotherm model. The binding of Cd to bacterial cells may be caused by the presence of different functional groups such as carboxyl, amide, and phosphate on cell surface, which was confirmed by the Fourier transform infrared-attenuated total reflectance spectra. Moreover, these strains decreased the Cd bioaccessibility by 44.7-46.8% in the in vitro digestion model. These findings indicate that P. pentosaceus FB145 and FB181 are novel potent biosorbent for preventing cadmium toxicity and reducing its absorption into the human body.

Pediococcus pentosaceus, a future additive or probiotic candidate

“…P. pentosaceus not only affected the substance absorption and excretion of the intestine but also upregulated toxic substance decomposition by the detoxification ability of the liver, such as reducing blood ammonia, heavy metal ion, and endotoxin levels [49]. Le and Yang [50] carried out experiments to show that P. pentosaceus FB145 and FB181, derived from fermented seafood, were capable of reducing the toxicity of cadmium (Cd). They found that Cd combined with bacterial cells by specific several functional groups and thus decreased Cd bioaccessibility in vitro to 44.7-46.8%.…”

Biosorption: A Review of the Latest Advances

“…The Pediococcus pentosaceus FB145 and FB181 strains, which can be considered as probiotic microorganisms, were suggested as potent biosorbents for preventing cadmium toxicity and reducing its absorption into the human body [97]-one more utility of biosorption, in this case, directly related to human health.…”

Sustainable microbial cell nanofactory for zinc oxide nanoparticles production by zinc-tolerant probiotic Lactobacillus plantarum strain TA4

“…Due to these attributes, strain TA4 possessed an advantage in its biotechnological application in the bioremediation, food, and pharmaceutical industry. Moreover, its ability to bind Zn 2+ would be useful in preventing excessive dietary Zn 2+ toxicity in animals and human gut [67] and in the removal of high concentration of Zn 2+ from consumption of water and liquid food [20]. Notably, zinc-enriched LAB was reported to possess beneficial effects on living organisms [50].…”