Biomechanical evaluation on tendon reinsertion by comparing trans-osseous suture and suture anchor at different stages of healing: Experimental study on rabbits

Barros, Rogério Meira; Matos, Marcos Almeida; Neto, Arnaldo Amado Ferreira; Benegas, Eduardo; Guarniero, Roberto; Pereira, César Augusto Martins; Neto, Raul Bölliger

doi:10.1016/j.jse.2010.03.008

Cited by 2 publications

(2 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The scores of insertion continuity and cell organization of the SA group were significantly higher than TO at 4‐week post repair. This finding agreed to a previous study on rabbit that showed the end‐point healing of the SA repair was comparable to that of the TO group, but SA group showed a faster healing at 3‐week post repair (Barros et al., 2010). It has been reported the SA repair underwent greater motion at the tendon‐bone interface than TO, which might result in mechanical stimulations at the interface (Ahmad et al., 2005).…”

Section: Discussionsupporting

confidence: 92%

See 1 more Smart Citation

Application of suture anchors for a clinically relevant rat model of rotator cuff tear

Liu

Yao

et al. 2022

J Tissue Eng Regen Med

View full text Add to dashboard Cite

Current rat model of rotator cuff (RC) tear could not mimic the suture anchor (SA) repair technique in the clinical practice. We designed a novel SA for RC repair of rats to establish a clinically relevant animal model. Small suture anchors that fit the rat shoulder were assembled. 60 rats were assigned to the transosseous (TO) repair group or SA repair group (n = 30/group). Micro-computed tomography (Micro-CT) scanning, biomechanical test and histological analysis were implemented at 2, 4, and 8-week post-repair. The failure load and stiffness in the SA group were significantly higher than those of TO group at 4-week post-repair. Micro-computed tomography analysis showed the bone mineral density and trabecular thickness of the SA group were significantly lower than those of TO group. The SA group showed a better insertion continuity at 4-week post-repair compared to TO group. No significant difference in gait parameters was found between groups. Therefore, SA repair is applicable for the rat model of RC tears. The SA repair achieved superior RC tendon healing, but more extensive initial bone damage compared to TO repair, while the shoulder function was comparable. This model could replicate the current repair technique in the clinical situation and be considered for future preclinical studies on healing enhancement for RC tears. Statement of Clinical Significance: With high clinical relevance, this model may facilitate the translation from an animal study into clinical trials.

show abstract

Section: Discussionsupporting

confidence: 92%

“…The surgical procedure was adapted from previous studies (Barros et al., 2010; Kang et al., 2013). A hole (Ø 0.9 mm, 3 mm depth) was created with a drill bit at 45° to the long axis of humerus, in which the SA was inserted.…”

Section: Methodsmentioning

confidence: 99%