Purpose of review
Mature B cell lymphomas bearing concurrent chromosomal rearrangement of MYC/8q24 and BCL2/18q21 are associated with an aggressive clinical course and resistance to conventional chemotherapy. This review summarizes the recent literature regarding the clinical and pathologic features of Double-hit lymphomas and outlines current questions about the most accurate and inclusive definition of the disease.
Comprehensive evaluation of large series of aggressive mature B cell neopl…
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