Biological nanoscale fluorescent probes: From structure and performance to bioimaging

Wan, Jiafeng; Zhang, Xiaoyuan; Zhang, Kai; Su, Zhiqiang

doi:10.1515/revac-2020-0119

Cited by 21 publications

(10 citation statements)

References 102 publications

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“…Subnanometer metal nanoclusters (NCs) have gained increasing attention in the last decade due to their applicability in biocatalysis, bioimaging, and biosensing. Noble metal NCs possess high biocompatibility, chemical stability, low toxicity, and low photobleaching [ 1 ]. This set of properties allows them to be used both in vitro and in vivo.…”

Section: Introductionmentioning

confidence: 99%

Silver Cluster Interactions with Tyrosine: Towards Amino Acid Detection

Buglak

Kononov

2022

IJMS

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Tyrosine (Tyr) is involved in the synthesis of neurotransmitters, catecholamines, thyroid hormones, etc. Multiple pathologies are associated with impaired Tyr metabolism. Silver nanoclusters (Ag NCs) can be applied for colorimetric, fluorescent, and surface-enhanced Raman spectroscopy (SERS) detection of Tyr. However, one should understand the theoretical basics of interactions between Tyr and Ag NCs. Thereby, we calculated the binding energy (Eb) between Tyr and Agnq (n = 1–8; q = 0–2) NCs using the density functional theory (DFT) to find the most stable complexes. Since Ag NCs are synthesized on Tyr in an aqueous solution at pH 12.5, we studied Tyr−1, semiquinone (SemiQ−1), and Tyr−2. Ag32+ and Ag5+ had the highest Eb. The absorption spectrum of Tyr−2 significantly red-shifts with the attachment of Ag32+, which is prospective for colorimetric Tyr detection. Ag32+ interacts with all functional groups of SemiQ−1 (phenolate, amino group, and carboxylate), which makes detection of Tyr possible due to band emergence at 1324 cm−1 in the vibrational spectrum. The ground state charge transfer between Ag and carboxylate determines the band emergence at 1661 cm−1 in the Raman spectrum of the SemiQ−1–Ag32+ complex. Thus, the prospects of Tyr detection using silver nanoclusters were demonstrated.

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Section: Introductionmentioning

confidence: 99%

Silver Cluster Interactions with Tyrosine: Towards Amino Acid Detection

Buglak

Kononov

2022

IJMS

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“…Recently, fluorescent carbon-dots (CDs) emerging as a new class of inorganic phosphors have attracted increasing attention [ 16 – 19 ]. Due to their obvious merits of facile and cheap preparation, excellent fluorescence characters, CDs have demonstrated many promising applications such as chemo/biosensing, bioimaging, catalysis, and optoelectronic devices [ 20 – 24 ]. Specially, most of the reported CDs are no/low toxic and biocompatible, and have been demonstrated great potential in biological-relevant fields [ 25 ].…”

Section: Introductionmentioning

confidence: 99%

Fluorescent carbon-dots enhance light harvesting and photosynthesis by overexpressing PsbP and PsiK genes

et al. 2021

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Background Fluorescent carbon-dots (CDs) with multifaceted advantages have provided hope for improvement of crop growth. Near infrared (NIR) CDs would be more competitive and promising than short-wavelength emissive CDs, which are not directly utilized by chloroplast. The molecular targets and underlying mechanism of these stimulative effects are rarely mentioned. Results NIR-CDs with good mono-dispersity and hydrophily were easily prepared by a one-step microwave-assisted carbonization manner, which showed obvious UV absorptive and far-red emissive properties. The chloroplast-CDs complexes could accelerate the electron transfer from photosystem II (PS II) to photosystem I (PS I). NIR-CDs exhibited a concentration-dependent promotion effect on N. benthamiana growth by strengthening photosynthesis. We firstly demonstrated that potential mechanisms behind the photosynthesis-stimulating activity might be related to up-regulated expression of the photosynthesis and chloroplast synthesis related genes, among which PsbP and PsiK genes are the key regulators. Conclusion These results illustrated that NIR-CDs showed great potential in the applications to increase crop yields through ultraviolet light harvesting and elevated photosynthesis efficiency. This work would provide a theoretical basis for the understanding and applications of the luminescent nanomaterials (not limited to CDs) in the sunlight conversion-related sustainable agriculture. Graphic abstract

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“…Several precursors and syn thetic approaches have been investigated, and the research is still ongoing to reach its full potential. [176][177][178][179] Scientists world wide have contributed experimental investigations on synthetic precursors and synthesis methods. [15,[20][21][22][23]…”

Section: Brief History Of Cdsmentioning

confidence: 99%

Recent Progress and Future Perspectives of Carbon Dots in the Detection, Degradation, and Enhancement of Drugs

Korah

Chacko

Abraham

et al. 2022

Part & Part Syst Charact

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for maximum solar energy conversion. Due to the broad light absorbance, photo luminescence (PL) properties, and elec tron transfer capability, CDs alone and as composites with other species can act as excellent candidates for the degradation of organic pollutants. CDs have a healthy competition between traditional semicon ductors in several aspects such as reduced cost, easy functionalization, biocompat ibility, highly tunable PL, inertness, and resistance to photobleaching, in which CDs are almost in the winning stage. [8,9] Drugs play an inevitable role in main taining human health and wellbeing. The harsh reality is that the high chem ical stability and low biodegradability of pharmaceuticals, along with an increase in consumption patterns, cause a signifi cant threat to aquatic life and the whole food chain. The active ingredients, pre servatives, radioactive components, and solvents used in the drug can act on unin tended targets. This hazardous material released to the environ ment due to various human activities are accumulative and can cause serious health issues to all living beings. [10,11] The sudden increase in the global emissions of antibiotics is attributed to their increasing overuse and misuse, along with the ineffective ness of existing degradation methods. It is a great relief that the CDs have the potential of detecting and degrading these phar maceuticals without hurting the green planet. It is essential to safeguard nature without causing everlasting scars and wounds.The detection of pharmaceuticals in drinking water necessi tates developing environmentfriendly methods and materials for their safe discharge. There are several reports of the syn thesis of CDs for the degradation and sensing of drugs. Further more, CDs have been used for the enhancement of the activity of antibiotics. Despite the growing focus on several other appli cations on CDs, there is no review giving special attention to the reported CDdrug relations in the literature. In this review, we have made a small step toward summarizing the interac tion between CDs and drugs, concentrating mainly on applica tions, including detection, degradation, and enhancement of drugs. The review is primarily divided into three sections after a brief note on CDs' history, synthesis approaches, and modifi cation methods. First section deals with the potential applica tion of CDs in detecting or sensing drugs. It is followed by the development of CD/photocatalyst composite for the photodeg radation of pharmaceutical products in the second section. The third section of the review is dedicated to the enhanced activity attained when CDs are conjugated with drugs.Carbon dots (CDs) are new types of nanoparticles with sizes less than 10 nm in diameter. CDs with their unique properties can detect, degrade, and surprisingly enhance drugs. This review focuses on three major aspects of CDdrug interactions: detection, degradation, and enhancement of drugs using CDs. The review begins with a brief account of the significant development milestones, the sy...

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Biological nanoscale fluorescent probes: From structure and performance to bioimaging

Cited by 21 publications

References 102 publications

Silver Cluster Interactions with Tyrosine: Towards Amino Acid Detection

Silver Cluster Interactions with Tyrosine: Towards Amino Acid Detection

Fluorescent carbon-dots enhance light harvesting and photosynthesis by overexpressing PsbP and PsiK genes

Recent Progress and Future Perspectives of Carbon Dots in the Detection, Degradation, and Enhancement of Drugs

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