2011
DOI: 10.1055/s-0030-1250499 View full text |Buy / Rent full text
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Abstract: We consider the PeriGuard Repair Patch® a viable alternative to synthetic materials for diaphragm replacement. Moreover, we advise carrying out cautious follow-up in patients undergoing extensive oncological resection to learn more about the biological behavior of the bovine PeriGuard Repair Patch® after diaphragmatic repair.

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“…[3][4][5][6][7] Right-sided CDA has a high mortality rate in comparison to right-sided CDH (95-98% versus 50-70%). [2][3][4][5][6][7]9,10 The present report details a unique case of right-sided CDA with complete hemidiaphragmatic agenesis associated with impaired development of the thoracic intercostal muscles and oesophageal mesentery. The defect was repaired using an autologous living bio-tissue flap to facilitate the development of a compliant neo-diaphragm that would provide effective pleuroperitoneal separation.…”
Section: Discussionmentioning
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“…[3][4][5][6][7] Right-sided CDA has a high mortality rate in comparison to right-sided CDH (95-98% versus 50-70%). [2][3][4][5][6][7]9,10 The present report details a unique case of right-sided CDA with complete hemidiaphragmatic agenesis associated with impaired development of the thoracic intercostal muscles and oesophageal mesentery. The defect was repaired using an autologous living bio-tissue flap to facilitate the development of a compliant neo-diaphragm that would provide effective pleuroperitoneal separation.…”
Section: Discussionmentioning
“…This is not unlike the concept of an underlay patch in treatment of large abdominal ventral hernias. 16 In cases #2, #3, and #4 there was remaining diaphragmatic defect despite attempts at primary repair. In cases #3 and #4 there was a contaminated field with bowel perforation in case #3 and empyema and bile spillage in case #4.…”
Section: Discussionmentioning
“…5 It demonstrated high tensile strength, elasticity, and was easy to manipulate. The patch has good biocompatibility, allowing ingrowth of natural tissue and minimal risk of infection.…”
Section: Discussionmentioning
“…The patch has good biocompatibility, allowing ingrowth of natural tissue and minimal risk of infection. 5 These qualities, combined with the possibility of microtears in a reoperative setting, prompted the selection of a bovine pericardium to repair the DH in this patient. Although the long-term outcomes remain uncertain, this case demonstrates the successful use of a bovine pericardium to repair a DH.…”
Section: Discussionmentioning