Biological effects of diethylene glycol (DEG) and produced waters (PWs) released from offshore activities: A multi-biomarker approach with the sea bass Dicentrarchus labrax

Gorbi, Stefania; Benedetti, Maura; Claudia, Virno Lamberti; Pisanelli, Barbara; Moltedo, Ginevra; Regoli, Francesco

doi:10.1016/j.envpol.2009.05.021

Cited by 24 publications

(5 citation statements)

References 41 publications

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“…Another challenge that the SB approach presents is the assumption that the ecotoxicity of PW within compound groups is the sum of individual toxicities and that PW toxicity is not matrix related. Hence, synergistic and antagonistic interactions are assumed to be either negligible or to cancel each other out (Johnsen et al, 2000;Stefania et al, 2009), which is in accordance with what has been found for mixtures with more than five chemicals present (Karman et al, 1996). However, studies of PW found indications of increased toxicity when adding PCs to synthetic PW (Bento & Campos, 2020;Tornambè et al, 2012), most likely due to increased solubility of oil-associated compounds.…”

Section: Challenges Of the Sb Approachsupporting

confidence: 78%

Critical review of the OSPAR risk‐based approach for offshore‐produced water discharges

Nielsen

Baun

Andersen

et al. 2022

Integr Envir Assess & Manag

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The management of produced water (PW) discharges from offshore oil and gas installations in the North Atlantic is under the auspices of OSPAR (Oslo/Paris convention for Protection of the Marine Environment of the North‐East Atlantic). In 2010, OSPAR introduced the risk‐based approach (RBA) for PW management. The RBA includes a hazard assessment estimating PW ecotoxicity using two approaches: whole‐effluent toxicity (WET) and substance‐based (SB). Set against the framework of the WET and SB approach, we conducted a literature review on the magnitude and cause of PW ecotoxicity, respectively, and on the challenges of estimating these. A large variability in the reported magnitude of PW WET was found, with EC50 or LC50 values ranging from <1% to >100%, and a median of 11% (n = 301). Across the literature, metals, hydrocarbons, and production chemicals were identified as causing ecotoxicity. However, this review reveals how knowledge gaps on PW composition and high sample and species dependency of PW ecotoxicity make clear identification and generalization difficult. It also highlights how limitations regarding the availability and reliability of ecotoxicity data result in large uncertainties in the subsequent risk estimates, which is not adequately reflected in the RBA output (e.g., environmental impact factors). Thus, it is recommended to increase the focus on improving ecotoxicity data quality before further use in the RBA, and that WET should play a more pronounced role in the testing strategy. To increase the reliability of the SB approach, more attention should be paid to the actual composition of PW. Bioassay‐directed chemical analysis, combining outcomes of WET and SB in toxicity identification evaluations, may hold the key to identifying drivers of ecotoxicity in PW. Finally, an uncertainty appraisal must be an integrated part of all reporting of risk estimates in the RBA, to avoid mitigation actions based on uncertainties rather than reliable ecotoxicity estimations. Integr Environ Assess Manag 2022;00:1–16. © 2022 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals LLC on behalf of Society of Environmental Toxicology & Chemistry (SETAC).

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Section: Challenges Of the Sb Approachsupporting

confidence: 78%

Critical review of the OSPAR risk‐based approach for offshore‐produced water discharges

Nielsen

Baun

Andersen

et al. 2022

Integr Envir Assess & Manag

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“…Environmental contamination by DEG is of worldwide concern because of its toxicity to living organisms, for example, mice and humans [3][4][5][6]. DEG environmental contamination has been reported, especially in water [7].…”

Section: Introductionmentioning

confidence: 99%

Diethylene glycol removal by Echinodorus cordifolius (L.): The role of plant–microbe interactions

Sriprapat

Kullavanijaya

Techkarnjanaruk

et al. 2011

Journal of Hazardous Materials

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“…Regarding the MN, their occurrence is an irreversible genotoxic event that reflects an accumulation of DNA breakages during cell cycle processes (Gorbi et al 2009;Bolognesi and Fenech 2012). The micronucleus test is frequently used to evaluate the genotoxicity of contaminants due to its simplicity, reliability and sensitivity (Ayllon and Garcia-Vazquez 2000) in vertebrates (Çelik et al 2005;Lajmanovich et al 2005;Hui Yin et al 2008;Hussain et al 2012) and invertebrate species (Bolognesi and Fenech 2012), and rarely applied in reptiles (mainly turtles and (Poletta et al 2009;Strunjak-Perovic et al 2010;Poletta et al 2011).…”

Section: Studied Biomarkersmentioning

confidence: 99%

“…Micronucleus (MN) frequencies were measured following Gorbi et al (2009). Blood samples were exposed to fixative solution changes before setting up blood smears coloured with ethidium bromide (2 μg/ml).…”

Section: Biomarkers Assaysmentioning

confidence: 99%

Biological responses in pesticide exposed lizards (Podarcis siculus)

et al. 2021

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The release of contaminants as herbicides, fungicides and insecticides into the environment has been listed as one of the six major contributors to the global decline of reptiles. Although reptiles may face severe risk from contaminants due to their ecology and physiology, they are currently less studied than other vertebrate groups. In the present work, we investigated if and how different types of field treatment (conventional and organic) affected the health status of Italian wall lizard (Podarcis siculus) individuals in central Italy. We chose a multi-biomarker approach that evaluated the biological responses of lizards to the treatment by means of AChE activity in the nervous system, biotransformation enzymes activities and oxidative stress in the liver, micronuclei frequency measured in the erythrocytes, and rate of intestinal parasitic infection. Our findings showed evidence of effects of treatment in conventional areas and between sexes with significant oxidative stress due to hydroxyl radicals, that caused DNA damage. No difference of intestinal parasite infections was found among treatments. Podarcis siculus seems to be a good bioindicator in ecotoxicological studies and potentially in risk assessment of pesticides, although further analyses in laboratory and in the field are needed to achieve more accurate quantification of specific pesticide effects in relation to known exposure history and to understand if other mechanisms were involved in the toxicity and detoxification process of pesticides for this species.

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Biological effects of diethylene glycol (DEG) and produced waters (PWs) released from offshore activities: A multi-biomarker approach with the sea bass Dicentrarchus labrax

Cited by 24 publications

References 41 publications

Critical review of the OSPAR risk‐based approach for offshore‐produced water discharges

Critical review of the OSPAR risk‐based approach for offshore‐produced water discharges

Diethylene glycol removal by Echinodorus cordifolius (L.): The role of plant–microbe interactions

Biological responses in pesticide exposed lizards (Podarcis siculus)

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