Biological Characterization of Ovarian Granulosa Cell Tumours of Slaughtered Cattle: Assessment of Cell Proliferation and Oestrogen Receptors

Pérez‐Martínez, Claudia; Durán-Navarrete, A.J.; García‐Fernández, Rosa A.; Espinosa-Alvarez, J.; Diez, A. Escudero; García‐Iglesias, M. J.

doi:10.1016/j.jcpa.2003.09.007

Cited by 19 publications

(10 citation statements)

References 14 publications

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“…This tumour is comparatively rare in domestic mammals and it has been mainly described in the bitch, sow and mare [36] . Pérez-Martınez et al [34] reported a GCT frequency of 0.74% in 1489 reformed cows.…”

Section: Discussionmentioning

confidence: 99%

“…The microscopic examination performed on the fragments of four ovarian tumours found in this study revealed that in three cases, it was the Granulosa Cell Tumour (GCT), which is a type of sex cord-stromal tumour, composed primarily of neoplastic granulosa cells [32] , and it is the most common bovine ovarian tumour in cattle [32][33][34][35] . In one case, it was the cystadenoma.…”

Section: Discussionmentioning

confidence: 99%

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Cezayir’de El-Harrach Kesimevinde Kesilen İneklerdeki Genital Kanal Patolojileri

Mimoune¹,

Kaidi²,

Azzouz³

et al. 2016

Kafkas Univ Vet Fak Derg

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The aim of this study was to determine genital organ disorders in 2025 cows at El-Harrach abattoir in the capital of Algeria and to describe the microscopic changes associated with these cases. The results obtained showed a high incidence of slaughtered pregnant cows (16.49%). Majority of these cases were at the early gestation. The most frequently encountered defects were ovarian cyst, uterine infection, and inflammatory salpinx, which proved that contamination and infection are always present in the cowsheds from where animals were brought. Other observed abnormalities were cervicitis, mucometra, double cervix, unicornis uterus, horn malformation, uterine tumour, triple cervix (which is a new finding in the world), salpinx adhesion, pyosalpinx, hydrosalpinx, ovarobursal adhesion, ovarian inactivity, ovarian inflammatory changes, ovarian tumour and parovarian cysts. ÖzetBu çalışmanın amacı Cezayir'in başşehrinde yer alan El-Harrach kesimevinde kesilen 2025 inekte gözlenen genital kanal bozukluklarını belirlemek ve bu vakalarla alakalı mikroskopik değişiklikleri tanımlamaktır. Sonuçlar çok sayıda gebe hayvanın (%16.49) kesime gönderildiğini ortaya koymuştur. Bu vakaların da çoğu gebeliğin erken dönemlerindeydi. En sık karşılaşılan bozukluklar ovaryum kistleri, uterus enfeksiyonu ve salfinks yangısıydı. Bu durum kesim için getirilen hayvanların getirildikleri ahırlarda enfeksiyonun ve kontaminasyonun sürekli olduğunu göstermekteydi. Diğer gözlenen bozukluklar servisitis, mukometra, çift serviks, unicornis uterus, rahim boynuz malformasyonları, uterus tümörü, triple serviks (yeni bir bulgu olarak), salfinks yapışması, pyosalfinks, hidrosalfinks, ovarobursal yapışma, ovaryum inaktivitesi, ovaryumun yangısal değişimleri, ovaryum tümörü ve parovarian kistler olarak kaydedildi.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Cezayir’de El-Harrach Kesimevinde Kesilen İneklerdeki Genital Kanal Patolojileri

Mimoune¹,

Kaidi²,

Azzouz³

et al. 2016

Kafkas Univ Vet Fak Derg

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“…Granulosa cell tumours (GCTs) are the most common ovarian tumours in cattle (Kumamoto et al 1998;Perez-Martinez et al 2004). Cows with GCTs may show nymphomania and abnormal udder development (Leder et al 1988) or may not show any clinical signs (Zachary and Haliburton 1983;Inokuma et al 2006;Haneishi et al 2008).…”

Section: Introductionmentioning

confidence: 99%

Clinical diagnosis of bovine granulosa cell tumour in a Holstein cow using plasma anti-Müllerian hormone concentration: a case report

Okawa

Tomiki

Ishida³

et al. 2016

Journal of Applied Animal Research

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A 23-month-old Holstein cow had a multi-cystic and enlarged left ovary detected by rectal palpation and ultrasonography. The plasma anti-Müllerian hormone (AMH) concentration was 36.5 ng/ml, which is higher than normal. From the clinical history and plasma AMH levels, a granulosa cell tumour (GCT) was diagnosed. Affected ovary was removed by ovariectomy, and GCT was confirmed with histopathological findings. The cow was artificially inseminated at 145 days after ovariectomy, and conceived. The plasma AMH concentration declined at 224 days after removal of affected ovary to less than 0.1 ng/ml, and recovery of fertility was achieved. In conclusion, measurement of plasma AMH levels combined with rectal palpation and ultrasonography examinations could be useful in clinical diagnosis of bovine GCT. ARTICLE HISTORY

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“…Reported incidence and prevalence rates are <0.5% (Zemjanis et al. 1961) and 0.74% (Pe′rez‐Marti′nez et al. 2004), respectively.…”

Section: Introductionmentioning

confidence: 99%

Two Atypical Cases of Granulosa Cell Tumours in Belgian Blue Heifers

Meganck¹,

Govaere²,

Vanholder³

et al. 2010

Reprod Domestic Animals

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This paper describes two atypical cases of granulosa cell tumours (GCTs) in Belgian Blue heifers. In the first case, an 18-month-old heifer died after ovariectomy, and a granulosa-theca cell tumour was diagnosed post-mortem. The second heifer (31 months of age) was near term and was successfully treated surgically for a malignant granulosa cell tumour. Unfortunately, no further reproductive data are available, as the heifer was sold for slaughter. This is the first report describing GCTs in Belgian Blue beef cattle.

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Biological Characterization of Ovarian Granulosa Cell Tumours of Slaughtered Cattle: Assessment of Cell Proliferation and Oestrogen Receptors

Cited by 19 publications

References 14 publications

Cezayir’de El-Harrach Kesimevinde Kesilen İneklerdeki Genital Kanal Patolojileri

Cezayir’de El-Harrach Kesimevinde Kesilen İneklerdeki Genital Kanal Patolojileri

Clinical diagnosis of bovine granulosa cell tumour in a Holstein cow using plasma anti-Müllerian hormone concentration: a case report

Two Atypical Cases of Granulosa Cell Tumours in Belgian Blue Heifers

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