2019
DOI: 10.7150/jca.29611
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Abstract: The increase of both life expectancy of the Western industrialized population and cancer incidence with aging is expected to result in a rapid expansion of the elderly cancer population, including patients with epithelial ovarian cancer (EOC). Although the survival of patients with EOC has generally improved over the past three decades, this progress has yet to provide benefits for elderly patients. Compared with young age, advanced age has been reported as an adverse prognostic factor influencing EOC. However… Show more

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Cited by 8 publications
(4 citation statements)
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References 177 publications
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“…On the other hand, EOC consists of a heterogeneous group of neoplasms with multiple histologic subtypes (22). The differences of tumor biology may also be associated with inherent platinum resistance (23). It is worth noting that clear cell cancer constitutes a larger percentage of ovarian cancers in East Asia [20] .…”
Section: Discussionmentioning
confidence: 99%
“…On the other hand, EOC consists of a heterogeneous group of neoplasms with multiple histologic subtypes (22). The differences of tumor biology may also be associated with inherent platinum resistance (23). It is worth noting that clear cell cancer constitutes a larger percentage of ovarian cancers in East Asia [20] .…”
Section: Discussionmentioning
confidence: 99%
“…Several studies have shown that the prognosis of elderly patients with TC is relatively poor (20)(21)(22). In addition, the relationship between older age and poor survival prognosis has been reported in many types of cancer (23)(24)(25). Highly DTC is the only malignant tumor that has been included in TNM staging by the AJCC (26).…”
Section: Discussionmentioning
confidence: 99%
“…In addition, in multivariate analysis, it was also found that patients with tumor residues of more than 2 cm had a HR of 3.772 (CI 2.36-6.02), which means that at any time patients with residuals of more than 2 cm were 3.77 times faster to experience recurrence than with a group of patients with a residue of less than 2 cm. 11,12 The success of cytoreduction surgery as reflected by the size of the tumor residue has been consistently shown to be one of the most influential factors in disease-free and patient survival rates. Age factor is also associated with epithelial ovarian cancer recurrence.…”
Section: Discussionmentioning
confidence: 99%
“…There is no definite evidence of a relationship between the two. [11][12][13] The Kaplan Meier curve and log rank test showed that there was no significant difference in disease-free survival between the group of patients aged more than 60 years and the group of patients aged less than 60 years. This is not in accordance with previous studies which showed that ovarian cancer patients aged more than 60 years had a higher risk of recurrence than those aged less than 60 years.…”
Section: Discussionmentioning
confidence: 99%