2020
DOI: 10.3389/fonc.2020.00330
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: An increasing body of evidence supports the association of immune genes with tumorigenesis and prognosis of breast cancer (BC). This research aims at exploring potential regulatory mechanisms and identifying immunogenic prognostic markers for BC, which were used to construct a prognostic signature for disease-free survival (DFS) of BC based on artificial intelligence algorithms. Differentially expressed immune genes were identified between normal tissues and tumor tissues. Univariate Cox regression identified … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

0
29
0

Year Published

2020
2020
2023
2023

Publication Types

Select...
7
2
1

Relationship

1
9

Authors

Journals

citations
Cited by 31 publications
(29 citation statements)
references
References 60 publications
0
29
0
Order By: Relevance
“…CXCL12 binds primarily to CXCR4 which can cause a mass of signal routing including the immunity [ 46 ]. FREM1 has been authenticated as an immune-related gene which may be a potential target for immunotherapy in breast cancer and clear cell renal cell carcinoma [ 47 , 48 ]. The insulin-like growth factor 1 (IGF1) pathway has been proven to contribute to the suppression of immune tumor microenvironment (TME) in gynecologic cancers [ 49 ].…”
Section: Discussionmentioning
confidence: 99%
“…CXCL12 binds primarily to CXCR4 which can cause a mass of signal routing including the immunity [ 46 ]. FREM1 has been authenticated as an immune-related gene which may be a potential target for immunotherapy in breast cancer and clear cell renal cell carcinoma [ 47 , 48 ]. The insulin-like growth factor 1 (IGF1) pathway has been proven to contribute to the suppression of immune tumor microenvironment (TME) in gynecologic cancers [ 49 ].…”
Section: Discussionmentioning
confidence: 99%
“…The genes that were down‐regulated in at least four of the five cell lines are listed in Table 2 (Hayashi et al., 2020; Hu et al., 2016; Huang et al., 2020; Jian & Yang, 2020; J. Jiang et al., 2006; Jiao et al., 2020; Loilome et al., 2012; Mattarei et al., 2018; Peng et al., 2019; Shen et al., 2015; Suhr et al., 2007; Takada et al., 2006; Yang, Lai, et al., 2019; Zhang et al., 2020). It was observed that APOL1 and APOBR were down‐regulated in response to LPDS‐treatment (24 hr) in all five cell lines (Table 2 and Figure 2).…”
Section: Resultsmentioning
confidence: 99%
“…Recently, it has been reported that the low expression of CD1B was associated with poorer biochemical recurrence-free survival in prostate cancer [19]. Moreover, CD1B could be used as a biomarker for the prognosis of breast cancer [20], and the low expression of CD1B might lead to the metastatic recurrence of breast cancer [21]. In addition, Yuan et al [22] found that, the low expression of CD1B was related to the deterioration of lung adenocarcinoma.…”
Section: Discussionmentioning
confidence: 99%