Biogenic Calcium Phosphate from Fish Discards and By-Products

Fernández-Arias, Mónica; Álvarez-Olcina, Iago; Malvido-Fresnillo, Pablo; Vázquez, José Antonio; Boutinguiza, M.; Comesaña, R.; Pou, J.

doi:10.3390/app11083387

Cited by 9 publications

(15 citation statements)

References 46 publications

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“…2− [109]. The decreasing of the Ca/P ratio in all three cases with the increase of the calcination temperature could be attributed to a partial transformation of the HA phase in β-TCP and, consequently, to the formation of BCP compound.…”

Section: Elemental Compositionmentioning

confidence: 84%

“…Heavy metals (like Hg, Cd, and Pb), which are present in fishes, should be avoided in any products dedicated to humans because of their harmful effects, such as toxic or carcinogenic behavior. For the three fish species, the authors found out that the amount of these elements present in BCP powder was lower than the maximum permitted value for organic bone implant materials (Cd: 0.68 ppm, Pb: 1.6 ppm, Hg: 0.04 ppm) [109].…”

Section: Elemental Compositionmentioning

confidence: 88%

“…SEM images of BCP powders derived from Scorpaena scrofa, Trachurus, and Salmo salar fish bones calcined at two temperatures (750 and 950 °C, respectively) revealed the same porous-shaped structure in both cases. In addition, granules of irregular morphologies with a porous structure were also observed (Figure 3) [109]. In another study, SEM images of BCP powders obtained from cod fish bones annealed at 1000 °C presented a morphology both with round grains (with dimensions of 300-500 nm) and with much larger and more crystalline-looking ones (crystals with a needle-like aspect, 500-nm wide and several microns long).…”

Section: Morphological Characteristicsmentioning

confidence: 88%

“…SEM images of BCP powders derived from Scorpaena scrofa, Trachurus, and Salmo salar fish bones calcined at two temperatures (750 and 950 • C, respectively) revealed the same porous-shaped structure in both cases. In addition, granules of irregular morphologies with a porous structure were also observed (Figure 3) [109].…”

Section: Morphological Characteristicsmentioning

confidence: 98%

“…By alkaline hydrolysis, Fernández-Arias et al [109] obtained BCP from whole individuals of fish discards derived from aquaculture processing. The hydrolysis process was followed by a calcination treatment in a furnace at temperatures of 750 • C and 950 • C for 10 h (heating rate of 10 • C/min).…”

Section: From Fish Discards To Powder Preparationmentioning

confidence: 99%

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A Review on Biphasic Calcium Phosphate Materials Derived from Fish Discards

2021

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This review summarizes the results reported on the production of biphasic calcium phosphate (BCP) materials derived from fish wastes (i.e., heads, bones, skins, and viscera), known as fish discards, and offers an in-depth discussion on their promising potential for various applications in many fields, especially the biomedical one. Thus, considerable scientific and technological efforts were recently focused on the capability of these sustainable materials to be transformed into economically attractive and highly valuable by-products. As a consequence of using these wastes, plenty of beneficial social effects, with both economic and environmental impact, will arise. In the biomedical field, there is a strong and continuous interest for the development of innovative solutions for healthcare improvement using alternative materials of biogenic origin. Thus, the orthopedic field has witnessed a significant development due to an increased demand for a large variety of implants, grafts, and/or scaffolds. This is mainly due to the increase of life expectancy and higher frequency of bone-associated injuries and diseases. As a consequence, the domain of bone-tissue engineering has expanded to be able to address a plethora of bone-related traumas and to deliver a viable and efficient substitute to allografts or autografts by combining bioactive materials and cells for bone-tissue ingrowth. Among biomaterials, calcium phosphate (CaP)-based bio-ceramics are widely used in medicine, in particular in orthopedics and dentistry, due to their excellent bioactive, osteoconductive, and osteointegrative characteristics. Recently, BCP materials (synthetic or natural), a class of CaP, which consist of a mixture of two phases, hydroxyapatite (HA) and beta tricalcium phosphate (β-TCP), in different concentrations, gained increased attention due to their superior overall performances as compared to single-phase formulations. Moreover, the exploitation of BCP materials from by-products of fish industry was reported to be a safe, cheap, and simple procedure. In the dedicated literature, there are many reviews on synthetic HA, β-TCP, or BCP materials, but to the best of our knowledge, this is the first collection of results on the effects of processing conditions on the morphological, compositional, structural, mechanical, and biological properties of the fish discard-derived BCPs along with the tailoring of their features for various applications.

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Section: Elemental Compositionmentioning

confidence: 84%

Section: Elemental Compositionmentioning

confidence: 88%

Section: Morphological Characteristicsmentioning

confidence: 88%

Section: Morphological Characteristicsmentioning

confidence: 98%

Section: From Fish Discards To Powder Preparationmentioning

confidence: 99%

See 3 more Smart Citations

A Review on Biphasic Calcium Phosphate Materials Derived from Fish Discards

2021

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Sustainable Sources of Raw Materials for Additive Manufacturing of Bone‐Substituting Biomaterials

Putra

Zhou

Zadpoor

2023

Adv Healthcare Materials

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The need for sustainable development has never been more urgent, as the world continues to struggle with environmental challenges, such as climate change, pollution, and dwindling natural resources. The use of renewable and recycled waste materials as a source of raw materials for biomaterials and tissue engineering is a promising avenue for sustainable development. Although tissue engineering has rapidly developed, the challenges associated with fulfilling the increasing demand for bone substitutes and implants remain unresolved, particularly as the global population ages. This review provides an overview of waste materials, such as eggshells, seashells, fish residues, and agricultural biomass, that can be transformed into biomaterials for bone tissue engineering. While the development of recycled metals is in its early stages, we highlight the use of probiotics and renewable polymers to improve the biofunctionalities of bone implants. Despite the advances of additive manufacturing (AM), studies on AM waste‐derived bone‐substitutes are limited. It is foreseeable that AM technologies can provide a more sustainable alternative to manufacturing biomaterials and implants. The preliminary results of eggshell and seashell‐derived calcium phosphate and rice husk ash‐derived silica will likely pave the way for more advanced applications of AM waste‐derived biomaterials for sustainably addressing several unmet clinical applications.This article is protected by copyright. All rights reserved

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Circular bioeconomy ecosystems: Hydroxyapatite from fish waste at Rio de Janeiro

Xavier,

da Silva,

Alves

et al. 2024

Biofuels Bioprod Bioref

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The transition to a low‐carbon economy endangered the revenues of many oil‐dependent regions. This is the case in Rio de Janeiro state, Brazil, which has become highly dependent on oil and gas royalties since the 1970s. At the same time, the circular blue bioeconomy has emerged as a pathway for environmentally sound socioeconomic development. In such a context, a biological resource in many oil‐dependent regions is fish processing residue, from which high added‐value compounds can be obtained, such as collagen, hydroxyapatite, gelatin, lipids, enzymes, hydrolysates, and bioactive peptides. The present study aims to understand the potential for a future fish waste hydroxyapatite (FHAp) market in the state of Rio de Janeiro (SRJ). The methodological approach integrates technology roadmapping with market and innovation ecosystem assessment. We found that the main techniques for obtaining FHAp were chemical hydrolysis and calcination, and the most innovative and value‐added applications were biomaterial for tissue regeneration (BTR) and physical sunblock (PS). The mapping of SRJ companies showed that the state has qualified players in cosmetic and biomedical industries that could develop innovations in BTR and PS made of FHAp. However, the mapping also showed a gap in the FHAp extraction stage, which is essential for the value chain. To find and encourage players to compound this innovation ecosystem, the public power can therefore act as an articulator, providing financial incentives and creating infrastructural conditions, such as a waste pretreatment plant next to the state fishing pole.

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Biogenic Calcium Phosphate from Fish Discards and By-Products

Cited by 9 publications

References 46 publications

A Review on Biphasic Calcium Phosphate Materials Derived from Fish Discards

A Review on Biphasic Calcium Phosphate Materials Derived from Fish Discards

Sustainable Sources of Raw Materials for Additive Manufacturing of Bone‐Substituting Biomaterials

Circular bioeconomy ecosystems: Hydroxyapatite from fish waste at Rio de Janeiro

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