Arch Otolaryngol Head Neck Surg
 2011
DOI: 10.1001/archoto.2010.205
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Biofilm Formation on Silicone Tympanostomy Tubes With Polyvinylpyrrolidone Coating

Patrick J. Antonelli
1
,
Edith M. Sampson2,
C. Ojano-Dirain3

Abstract: Polyvinylpyrrolidone coating of TTs imparts resistance to P aeruginosa biofilm formation. The clinical impact of PVP on TTs may be attenuated by exposure to blood, but this will require study in clinical trials.

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Cited by 21 publications

(15 citation statements)
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“…When analyzing the prevalence of these types of otorrhea among the different ventilation tubes, there was no significant difference in their prevalence among the four tube types. Studies have shown that Microgel and Activent‐coated tubes reduce biofilm formation and otorrhea 14,15 . However, they did not differentiate between the severity of otorrhea, as in this study.…”
Section: Discussioncontrasting
confidence: 78%
“…Studies have shown that Microgel and Activent-coated tubes reduce biofilm formation and otorrhea. 14,15 However, they did not differentiate between the severity of otorrhea, as in this study. A possible explanation for our findings is that intractable otorrhea requires more aggressive management and may be due to patient-specific characteristics rather than to tubespecific qualities.…”
Section: Otorrheacontrasting
confidence: 70%
See 1 more Smart Citation
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…When analyzing the prevalence of these types of otorrhea among the different ventilation tubes, there was no significant difference in their prevalence among the four tube types. Studies have shown that Microgel and Activent‐coated tubes reduce biofilm formation and otorrhea 14,15 . However, they did not differentiate between the severity of otorrhea, as in this study.…”
Section: Discussioncontrasting
confidence: 78%
“…Studies have shown that Microgel and Activent-coated tubes reduce biofilm formation and otorrhea. 14,15 However, they did not differentiate between the severity of otorrhea, as in this study. A possible explanation for our findings is that intractable otorrhea requires more aggressive management and may be due to patient-specific characteristics rather than to tubespecific qualities.…”
Section: Otorrheacontrasting
confidence: 70%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The negligible effect of PVP coating on biofilm development rules out its possible role in the promotion in biofilm formation. Moreover, PVP coating has been reported to hinder biofilm formation by P. aeruginosa on silicone tubes . The stronger effect of AgNPs than Ag + at an equivalent concentration is likely due to the presence of inorganic ligands (e.g., chloride and phosphate) and organic matter [e.g., soluble microbial products (SMPs) and EPS], which can reduce the bioavailability and effect of Ag + to a greater extent than AgNPs. , …”
Section: Resultsmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“… 15 Furthermore, the silicone component of Sl may act as a potential nidus of infection, leading to subsequent graft loss and rejection. 16 …”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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