Biodegradation and toxicity reduction of nonylphenol, 4-tert-octylphenol and 2,4-dichlorophenol by the ascomycetous fungus Thielavia sp HJ22: Identification of fungal metabolites and proposal of a putative pathway

Mtibaà, Rim; Ezzanad, Abdellah; Aranda, Elisabet; Pozo, Clementina; Ghariani, Bouthaina; Moraga, Javier; Nasri, Monçef; Cantoral, Jesús M.; Garrido, Carlos; Mechichi, Tahar

doi:10.1016/j.scitotenv.2019.135129

Cited by 50 publications

(18 citation statements)

References 68 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…For instance, strains of Thielavia sp. and Hanerochaete chrysosporium can efficiently degrade phenols (Lu et al, 2009;Mtibaà et al, 2020). Therefore, it is expected that fungi could be effectively applied for the deep purification of recalcitrant organic pollutants.…”

Section: Introductionmentioning

confidence: 99%

Improving Azo Dye Decolorization Performance and Halotolerance of Pichia occidentalis A2 by Static Magnetic Field and Possible Mechanisms Through Comparative Transcriptome Analysis

Wang

Ning

et al. 2020

Front. Microbiol.

View full text Add to dashboard Cite

A halotolerant yeast, Pichia occidentalis A2, was recently isolated that can decolorize various azo dyes. The azo dye decolorization performance of this strain was characterized, including the degradation pathway and detoxification effects of this yeast. Additionally, the effect of static magnetic field (SMF) on this decolorization process was investigated. Activities of key enzymes were analyzed to estimate the change of metabolic activity. Furthermore, possible mechanisms were analyzed through detecting differentially expressed genes between yeast A2 in the absence and presence of SMF. The results indicated that yeast A2 displayed the optimal decolorization performance when the concentrations (in g/L) of glucose, (NH 4) 2 SO 4 , yeast extract, and NaCl were 4.0, 1.0, 0.1, and ≤30.0, respectively. Meanwhile, the optimal rotation speed, temperature, and pH were 160 rpm, 30 • C, and 5.0, respectively. Acid Red B was decolorized and detoxified by yeast A2 through successive steps, including cleavage of the naphthalene-amidine bond, reductive deamination, oxidative deamination/desulfurization, open-loop of hydroxy-substituted naphthalene, and tricarboxylic acid cycle. The dye decolorization efficiency and halotolerance of yeast A2 were enhanced by 206.3 mT SMF. The activities of manganese peroxidase, and laccase were elevated 1.37-and 1.16-fold by 206.3 mT SMF, but lignin peroxidase activity showed little change. It was suggested from the transcriptome sequence that the enhanced halotolerance might be related to the upregulated genes encoding the enzymes or functional proteins related to intracellular synthesis and accumulation of glycerol.

show abstract

Section: Introductionmentioning

confidence: 99%

Improving Azo Dye Decolorization Performance and Halotolerance of Pichia occidentalis A2 by Static Magnetic Field and Possible Mechanisms Through Comparative Transcriptome Analysis

Wang

Ning

et al. 2020

Front. Microbiol.

View full text Add to dashboard Cite

show abstract

“…Mtibaá et al evaluated the ability of the ascomycetes Thielavia sp. HJ22 to remove phenolic xenobiotics, i.e., 2,4-dichlorophenol was found to be metabolized by the formation of hydroxylated and oxidized derivatives [ 35 ].…”

Section: Resultsmentioning

confidence: 99%

“…The removal of 2,4-dichlorophenol by Thielavia sp. was conducted by the formation of hydroxylated and oxidized metabolites [ 35 ]. Furthermore, ligninolytic enzymes were found to play a key function in the degradation of chlorophenols.…”

Section: Introductionmentioning

confidence: 99%

Biodegradation of Chloroxylenol by Cunninghamella elegans IM 1785/21GP and Trametes versicolor IM 373: Insight into Ecotoxicity and Metabolic Pathways

Nowak

Zawadzka

Szemraj

et al. 2021

IJMS

View full text Add to dashboard Cite

Chloroxylenol (PCMX) is applied as a preservative and disinfectant in personal care products, currently recommended for use to inactivate the SARS-CoV-2 virus. Its intensive application leads to the release of PCMX into the environment, which can have a harmful impact on aquatic and soil biotas. The aim of this study was to assess the mechanism of chloroxylenol biodegradation by the fungal strains Cunninghamella elegans IM 1785/21GP and Trametes versicolor IM 373, and investigate the ecotoxicity of emerging by-products. The residues of PCMX and formed metabolites were analysed using GC-MS. The elimination of PCMX in the cultures of tested microorganisms was above 70%. Five fungal by-products were detected for the first time. Identified intermediates were performed by dechlorination, hydroxylation, and oxidation reactions catalysed by cytochrome P450 enzymes and laccase. A real-time quantitative PCR analysis confirmed an increase in CYP450 genes expression in C. elegans cells. In the case of T. versicolor, spectrophotometric measurement of the oxidation of 2,20-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) showed a significant rise in laccase activity during PCMX elimination. Furthermore, with the use of bioindicators from different ecosystems (Daphtoxkit F and Phytotoxkit), it was revealed that the biodegradation process of PCMX had a detoxifying nature.

show abstract

“…Doğaya verilen ksenobiyotik özellikli organik kimyasallar genel olarak uzun zincirli alkilfenoller ve klorofenoller; evlerde, ticari ve endüstriyel uygulamalarda yaygın olarak kullanılmaktadır [1,2]. Bu hammaddeler, alıcı ortamlara karıştığında mikro kirleticiler olarak değerlendirilmekte olup son zamanlarda daha dikkat çekici hale gelmiştir [3].…”

Section: Introductionunclassified

“…Klorofenoller çok düşük konsantrasyonlarda dahi suda tat ve koku problemi oluşturmaktadır. Ayrıca mikrokirletici olarak sularda bulunduklarında suda yaşayan canlılar ve insanlar için yüksek toksisite ve biyolojik birikime sahiptir [1,6,7]. Bu gibi olumsuz etkileri nedeniyle Dünya Sağlık Örgütü (WHO) tarafından fenol konsantrasyonu içme sularında 1 mg/L olarak sınırlandırılmıştır [8].…”

Section: Introductionunclassified

Aklime Edilmiş Aktif Çamur Mikroorganizmaları ile Sürekli Sistem Yukarı Akışlı Dolgulu Kolonda 2,4- Diklorofenol Gideriminin İncelenmesi

Deveci¹

2021

Ömer Halisdemir Üniversitesi Mühendislik Bilimleri Dergisi

View full text Add to dashboard Cite

Endüstriyel üretim sonrası ortaya çıkan atıksular alıcı ortamlara verilmeden önce atıksu içeriğinde bulunan kirlilik parametrelerinin deşarj kriterlerin altında arıtılması gerekmektedir. Fenol ve türevi olan kimyasal bileşikler endüstriyel üretim sonrası atıksular içerisinde yüksek konsantrasyonda bulunmaktadırlar. Bu fenol ve türevi bileşikleri içeren atıksular kanserojenik ve teratojenik etkilere sahiptir. Bu nedenle bu tip atıksuların alıcı ortamlara arıtılmadan deşarj edilmemesi gerekmektedir. Bu amaçla bu çalışmada 2,4-diklorofenol ile aklime edilmiş aktif çamur mikroorganizmalarının yukarı akışlı olarak poliüretan ile doldurulmuş kolonda 2,4diklorofenol giderimi incelenmiştir. Aklime edilmiş aktif çamur mikroorganizmaları poliüretan sünger parçaları üzerine immobilize edilmiş ve yukarı akışlı dolgulu kolonda 2,4dikolorofenolün sürekli sistemde 90 gün boyunca arıtımı incelenmiştir. Elde edilen sonuçlara göre en optimum 500 mg/L 2,4-dikolorofenol komsatrasyonunda %83 KOİ ve %86 fenol giderimi sağlanmıştır.

show abstract

Biodegradation and toxicity reduction of nonylphenol, 4-tert-octylphenol and 2,4-dichlorophenol by the ascomycetous fungus Thielavia sp HJ22: Identification of fungal metabolites and proposal of a putative pathway

Cited by 50 publications

References 68 publications

Improving Azo Dye Decolorization Performance and Halotolerance of Pichia occidentalis A2 by Static Magnetic Field and Possible Mechanisms Through Comparative Transcriptome Analysis

Improving Azo Dye Decolorization Performance and Halotolerance of Pichia occidentalis A2 by Static Magnetic Field and Possible Mechanisms Through Comparative Transcriptome Analysis

Biodegradation of Chloroxylenol by Cunninghamella elegans IM 1785/21GP and Trametes versicolor IM 373: Insight into Ecotoxicity and Metabolic Pathways

Aklime Edilmiş Aktif Çamur Mikroorganizmaları ile Sürekli Sistem Yukarı Akışlı Dolgulu Kolonda 2,4- Diklorofenol Gideriminin İncelenmesi

Contact Info

Product

Resources

About