2012
DOI: 10.1039/c2nr31281f
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Abstract: Biocompatible fluorescent organic nanoparticles with tunable photoluminescence were prepared via the one-pot oxidation of polydopamine and subsequently utilized for cell imaging.

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Cited by 469 publications
(272 citation statements)
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“…5 PDA-based materials were biomedically applied to biosensing, bioimaging, drug delivery, tissue engineering, theranostics, and cancer photothermal treatment. [6][7][8][9][10][11][12] Many materials such as carbon nanotubes, graphene oxide (GO) sheets, gold nanorods, and conjugated polymeric nanomaterials all exhibit considerable photothermal conversion effects. [13][14][15][16][17] However, carbon nanotubes and GO sheets have low degradability in vivo, whereas gold nanorods face the drawbacks of toxicity and high cost.…”
Section: Introductionmentioning
confidence: 99%
“…5 PDA-based materials were biomedically applied to biosensing, bioimaging, drug delivery, tissue engineering, theranostics, and cancer photothermal treatment. [6][7][8][9][10][11][12] Many materials such as carbon nanotubes, graphene oxide (GO) sheets, gold nanorods, and conjugated polymeric nanomaterials all exhibit considerable photothermal conversion effects. [13][14][15][16][17] However, carbon nanotubes and GO sheets have low degradability in vivo, whereas gold nanorods face the drawbacks of toxicity and high cost.…”
Section: Introductionmentioning
confidence: 99%
“…26 Although, the fluorescence property of eumelanins is known for more than 40 years and there is ongoing research to understand the interesting optical properties of these materials; 27−29 the fluorescence of PDA is largely unexplored. To our knowledge, only very recently Zhang et al 30 reported that purified PDA nanoparticles are fluorescent and can be used for cellular imaging.Here, we explored the intrinsic emission properties of PDA nanoparticles which were synthesized by oxidizing DA under different conditions and demonstrated that it can be used as turn-on type fluorescent reporter of DA existence. The introduced method is based on monitoring the visible light emission of in situ synthesized PDA nanoparticles, and it is capable to detect very low DA concentrations (detection limit is 40 nM).…”
mentioning
confidence: 99%
“…26 Although, the fluorescence property of eumelanins is known for more than 40 years and there is ongoing research to understand the interesting optical properties of these materials; 27−29 the fluorescence of PDA is largely unexplored. To our knowledge, only very recently Zhang et al 30 reported that purified PDA nanoparticles are fluorescent and can be used for cellular imaging.…”
mentioning
confidence: 99%
“…[25][26][27][28][29][30][31] Among them, the AIE or AIEE based FONs have attracted great research interest because they could overcome the notorious aggregation-caused quenching (ACQ) effect of most organic dyes. Different AIE or AIEE units such as siloles, [32][33][34] However, direct employment of AIE or AIEE based FONs for bioimaging has been proven problematic due to the strong hydrophobicity of most of AIE or AIEE units.…”
Section: -24mentioning
confidence: 99%