2019
DOI: 10.21577/1984-6835.20190072
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Abstract: Método Bioanalítico para o Fluazuron em Plasma Bovino e Sua Aplicação em Estudos de FarmacocinéticaResumo: Fluazuron é um regulador de crescimento de insetos pertencente à classe da benzofeniluréia que é comercializado para o controle do carrapato bovino. Embora os reguladores de crescimento sejam uma classe amplamente estudada, o número de artigos descrevendo métodos analíticos para determinar o fluazuron em amostras de plasma animal é reduzido. Para avaliar a característica farmacocinética do fluazuron em bo… Show more

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Cited by 3 publications
(4 citation statements)
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“…In Study II, we observed the same pattern of quick absorption and slow elimination of FLU as reported by Lopes et al [ 18 ] and Ferreira et al [ 22 ].…”
Section: Discussionsupporting
confidence: 88%
See 2 more Smart Citations
“…In Study II, we observed the same pattern of quick absorption and slow elimination of FLU as reported by Lopes et al [ 18 ] and Ferreira et al [ 22 ].…”
Section: Discussionsupporting
confidence: 88%
“…The use of FLU as ectoparasiticide and its pharmacokinetic parameters were described by Lopes et al [ 18 ] and Ferreira et al [ 22 ] for pour-on formulations in cattle (2.5 mg/kg, single dose). However, according to Flajs and Grabnar [ 36 ], although the comparison of pharmacokinetic parameters between different species and with different administration routes is not recommended, it is still possible to compare the average time when levels of the drug can be detected in the blood plasma.…”
Section: Discussionmentioning
confidence: 99%
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“…In order to study the pharmacokinetic characteristics of fluazuron in cattle, Ferreira et al (2019) evaluated and validated a method of liquid chromatography ultraviolet detection (LC-UV). The authors stated that fluazuron, administered topically to animals, with a dosage of 2.5mg kg-1, reached the systemic circulation and was absorbed (T max=48 Hs), remaining quantifiable in plasma levels for up to 14 days after treatment.…”
Section: Discussionmentioning
confidence: 99%