Bioactivity of Fe 2 O 3 -CaO-SiO 2 glass ceramics modified through the addition of P 2 O 5 and TiO 2

Wang, Yongya; Li, B.; Luo, Wenqin; Cao, Feng

doi:10.1016/j.ceramint.2017.02.080

Cited by 11 publications

(7 citation statements)

References 37 publications

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“…Fe 2 O 3 ‐CaO‐SiO 2 glass‐ceramics containing P 2 O 5 show good bioactivity, which has been confirmed by previous research . The cytotoxicity results show that PFCS glass‐ceramic samples display very weak cytotoxicity toward both the normal FHC cells and the malignant LoVo cells, and they do not have harmful effects on cell proliferation.…”

Section: Discussionsupporting

confidence: 81%

“…Fe 2 O 3 -CaO-SiO 2 glass-ceramics containing P 2 O 5 show good bioactivity, which has been confirmed by previous research. 21 The cytotoxicity results show that PFCS glassceramic samples display very weak cytotoxicity toward both the normal FHC cells and the malignant LoVo cells, and they do not have harmful effects on cell proliferation. However, their induction heating ability in the alternating magnetic field can effectively kill the LoVo cancer cells, and this killing effect has a certain relationship with the phosphorus content.…”

Section: Discussionmentioning

confidence: 95%

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P₂O₅‐Fe₂O₃‐CaO‐SiO₂ ferromagnetic glass‐ceramics for hyperthermia

Wang

Zhang

et al. 2018

Int J Applied Ceramic Tech

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Ferromagnetic glass‐ceramics are an important kind of thermoseed material for hyperthermia treatments. In order to investigate the applications of glass‐ceramics in magnetic hyperthermia, P2O5‐Fe2O3‐CaO‐SiO2 (PFCS) glass‐ceramics with different compositions were prepared by the sol‐gel method. The crystal phase, magnetic properties, induction heating ability, and cytotoxicity of the as‐prepared glass‐ceramics were investigated. The results show that all the samples exhibit low cytotoxicity and good induction heating ability. Moreover, it was found that the phosphorus content affected the crystal phase component of the sample, and thus influenced the induction heating ability. Results of the magnetic hyperthermia experiments showed that the PFCS glass‐ceramic samples induced significant cell death of the LoVo cancer cells. The highest cell death rate for sample B2P7 was more than 95%, which suggests good application prospects in the field of hyperthermia therapy.

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Section: Discussionsupporting

confidence: 81%

Section: Discussionmentioning

confidence: 95%

P₂O₅‐Fe₂O₃‐CaO‐SiO₂ ferromagnetic glass‐ceramics for hyperthermia

Wang

Zhang

et al. 2018

Int J Applied Ceramic Tech

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“…Calcium and hematite formed calcium ferrite when the pore‐forming agent content reached 40%. Glass‐ceramics containing these crystal phases are biocompatible making them feasible carriers, and hydrated silica formed on the surface of wollastonite and larnite provides favorable sites for apatite nucleation.…”

Section: Resultsmentioning

confidence: 99%

Immobilizing nitrifying bacteria with Fe₂O₃‐CaO‐SiO₂ porous glass‐ceramics

Yang

Wang

et al. 2018

Int J of Appl Glass Sci

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Nitrifying bacteria immobilized on Fe 2 O 3 -CaO-SiO 2 porous glass-ceramics have extensive application prospects for wastewater treatment. To study the effect of the pore structure on the immobilization, Fe 2 O 3 -CaO-SiO 2 porous glass-ceramics with different porosities and pore sizes were prepared by sintering and the addition of pore-forming agent. The pore size and apparent porosity can be controlled by the pore-forming agent content and their sizes. Appropriate amount of the pore-forming agent can promote the apparent porosity and increase the amount of immobilized nitrifying bacteria. The excess of the pore-forming agent can cause the formation of the new crystalline phases and reduce the amount of immobilized nitrifying bacteria. In this study, we demonstrate that Fe 2 O 3 -CaO-SiO 2 porous glass-ceramics with 30% pore-forming agent exhibit a moderate apparent porosity and good immobilization. This combination has good application prospects in the field of ammonia treatment in wastewater. K E Y W O R D Smicroorganism immobilization, nitrifying bacteria, pore-forming agent, porous glass-ceramics

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“…187 Also, adding P 2 O 5 to magnetic Fe 2 O 3 -CaO-SiO 2 glass-ceramics promoted the formation of a surface apatite layer (bioactivity) while eliciting low cytotoxicity in vitro. 188 Mesoporous lithium-ferrite-containing BGs synthesized through the sol-gel technique are another class of promising BGs for hyperthermia. Yazdanpanah et al 189 proved that these glasses are appropriate for use as thermoseeds.…”

Section: Magnetic Hyperthermiamentioning

confidence: 99%

A critical review of bioactive glasses and glass–ceramics in cancer therapy

Moeini

Chinijani

Khachatourian

et al. 2022

Int J of Appl Glass Sci

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There is an ongoing profound shift in using glass as a primarily passive material to one that instills active properties. We believe and demonstrate that bioactive glasses (BGs) and glass–ceramics (BGCs) as functional biomaterials for cancer therapy can transform the world of healthcare in the 21st century. Melt/gel‐derived BGs and BGCs can carry many exotic elements, including less common rare‐earth, and trigger highly efficient anticancer properties via the combination of radiotherapy, photothermal therapy, magnetic hyperthermia, along with drug or therapeutic ions delivery. The addition of these dopants modifies the bioactivity, imparts novel functionalities, and induces specific biological effects that are not achievable using other classes of biomaterials. In this paper, we have briefly reviewed and discussed the current knowledge on promising compositions, processing parameters, and applications of BGs and BGCs in treating cancer. We also envisage the need for further research on this particular, unique class of BGs and BGCs.

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Bioactivity of Fe 2 O 3 -CaO-SiO 2 glass ceramics modified through the addition of P 2 O 5 and TiO 2

Cited by 11 publications

References 37 publications

P₂O₅‐Fe₂O₃‐CaO‐SiO₂ ferromagnetic glass‐ceramics for hyperthermia

P₂O₅‐Fe₂O₃‐CaO‐SiO₂ ferromagnetic glass‐ceramics for hyperthermia

Immobilizing nitrifying bacteria with Fe₂O₃‐CaO‐SiO₂ porous glass‐ceramics

A critical review of bioactive glasses and glass–ceramics in cancer therapy

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Bioactivity of Fe 2 O 3 -CaO-SiO 2 glass ceramics modified through the addition of P 2 O 5 and TiO 2

Cited by 11 publications

References 37 publications

P2O5‐Fe2O3‐CaO‐SiO2 ferromagnetic glass‐ceramics for hyperthermia

P2O5‐Fe2O3‐CaO‐SiO2 ferromagnetic glass‐ceramics for hyperthermia

Immobilizing nitrifying bacteria with Fe2O3‐CaO‐SiO2 porous glass‐ceramics

A critical review of bioactive glasses and glass–ceramics in cancer therapy

Contact Info

Product

Resources

About

P₂O₅‐Fe₂O₃‐CaO‐SiO₂ ferromagnetic glass‐ceramics for hyperthermia

P₂O₅‐Fe₂O₃‐CaO‐SiO₂ ferromagnetic glass‐ceramics for hyperthermia

Immobilizing nitrifying bacteria with Fe₂O₃‐CaO‐SiO₂ porous glass‐ceramics