Bioactivity of a Ni-Free Ti-Based Metallic Glass

Abstract

In this study, a bone-like apatite layer was formed on a Ni-free Ti-based metallic glass. A two-step treatment method, i.e., hydrothermalelectrochemical treatment followed by pre-calcification treatment, was developed to prepare a bioactive surface on the Ti-based metallic glass. The results reveal that the combination of electrochemical-hydrothermal and pre-calcification treatments can accelerate nucleation and improve growth rate of apatite on Ti-based metallic glass in simulated body fluid (Hanks' solution). The reasons why the two-step treatment accelerates the nucleation and growth of apatite were also discussed.

Enhanced Mechanical Properties, Corrosion Behavior and Bioactivity of Ti-based Bulk Metallic Glasses with Minor Addition Elements

“…Ti-based BMGs are expected as one of the most important metallic materials in orthopedics and dental surgery due to their low Young's modulus, high fracture strength, excellent strength-to-weight ratio, good corrosion resistance and superior biocompatibility of titanium [1][2][3][4]. Recently, the developments of Ni-free Ti-Zr-Cu-Pd and Ti-Zr-Cu-Pd-Sn BMGs with high glassforming ability (GFA) make it possible to create newgeneration metallic biomedical materials with acceptable properties [5][6][7][8][9][10]. Usually, BMG materials catastrophically fracture once the main shear band initiates and propagates without any obstacle.…”

“…Therefore, bioactive treatment is not as easy as hydrothermal treatment for conventional Ti alloys [18]. A special two-step treatment including hydrothermal-electrochemical treatment followed by an immersion in Hanks' solution is effective to Ti-based BMGs [8]. In this study, corrosion behavior, mechanical properties and bioactivity of Ti 40 Zr 10 Cu 34 Pd 14 Sn 2 and Ti 40 Zr 10 Cu 33 Pd 14 Sn 2 M 1 (M = Au, Pt, Nb or Ta) were investigated.…”

Recent Progress in Ti-Based Metallic Glasses for Application as Biomaterials

“…After immersion of one day, a thin and homogeneous layer appears in the network surface ( Fig. 14(a)), 116) which is composed of Ca, P and O. The Ca/P ratio is identified to be 1.3 by EDS.…”

“…12(a). 116) A grown composite layer named as "graded intermediated layer" or "growing integrated layer (GIL)" 117) with a thickness of several hundred nanometers is formed in the hydrothermalelectrochemical treated Ti 40 Zr 10 Cu 36 Pd 14 metallic glass, as shown in Fig. 12(b).…”

“…12(b). 116) The outer layer (Layer 1 in Fig. 12(b)) is the porous and network layer formed by the reaction of the alloy components with the alkali solution.…”