Journal of Chromatography A 2012 DOI: 10.1016/j.chroma.2012.01.008 View full text
Yuanyuan Hou, Xuelin Cao, Linyi Dong, Liqiang Wang, Binfeng Cheng, Qian Shi, Xiaodong Luo, Gang Bai

Abstract: Although chromatographic fingerprinting combined with chemometrics, is a rational method for the quality control of traditional Chinese medicine (TCM), chemometrics cannot fully explore the relationship between chemical information and the efficacy of the potential activity. In the present work, a cell-based β₂ adrenergic receptor (β₂AR) agonist functional evaluation model coupled with high-performance liquid chromatography was developed to screen the potential β₂AR agonist components in the alkaloidal extract…

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