Bioactive soy isoflavones: extraction and purification procedures, potential dermal use and nanotechnology-based delivery systems

Nemitz, Marina Cardoso; Moraes, Renata Cougo; Koester, Letícia Scherer; Bassani, Valquíria Linck; Poser, Gilsane Lino von; Teixeira, Hélder Ferreira

doi:10.1007/s11101-014-9382-0

Cited by 36 publications

(18 citation statements)

References 109 publications

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“…Another important use of these technologies is related to the treatment of different microbiological infections, presenting antifungal, antibacterial, and antiviral activity. Altogether, the pharmaceutical application technologies are in accordance with the scientific literature that also reports the relevance of nanotechnology in a wide range of skin diseases [18,24,28,31,[58][59][60][61][62][63].…”

Section: Table 3 Patents Separated By Clusters After Examination Of supporting

confidence: 62%

Recent Patents Concerning the use of Nanotechnology-based Delivery Systems as Skin Penetration Enhancers

Medeiros-Neves

Nemitz

Fachel

et al. 2020

DDF

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: Nanotechnology-based delivery systems have been considered a promising approach for topical application, considering their characteristics of penetration into/across the skin. The present review aimed to evaluate the recent international scenario of patents concerning the use of nanotechnology- based delivery systems as skin penetration enhancers. A survey of recent patent documents was conducted by using the Espacenet patent database including the terms “skin” in the title and “promot* or enhanc* and penetrat* or absorp* or permeat*” and “nano*” with the truncation symbol (*) in the abstract of documents. A total of 110 patents were published from 2008 to 2018, with 94 technologies being considered. The results demonstrated an increase in innovations concerning nanotechnologybased delivery systems as skin penetration enhancers in recent years. Most patent applicants are from China (60.6%) and Korea (21.3%), and companies (68%) were the most prominent owners. The majority of patent applications (76%) were intended for cosmetic purposes; the types of products and nanostructures were also investigated. Overall results demonstrated the increased interest around the world in patenting products involving skin permeation promotion and nanotechnology for pharmaceutical and, mainly, for cosmetics purposes.

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Section: Table 3 Patents Separated By Clusters After Examination Of supporting

confidence: 62%

Recent Patents Concerning the use of Nanotechnology-based Delivery Systems as Skin Penetration Enhancers

Medeiros-Neves

Nemitz

Fachel

et al. 2020

DDF

Self Cite

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“…To obtain polyphenol‐rich extracts, it is necessary to purify the sample by removing impurities with column chromatography (Nemitz et al., ). Different types of adsorbents, such as silica gel, macroporous resins, Sephadex LH‐20, HW‐F40 Toyopearl resin polymer, and silica gel type 60 have been used to purify common bean polyphenols.…”

Section: Extraction Separation and Identification Methodsmentioning

confidence: 99%

Polyphenols in Common Beans (Phaseolus vulgaris L.): Chemistry, Analysis, and Factors Affecting Composition

Yang

Gan

et al. 2018

Comp Rev Food Sci Food Safe

112

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Common bean (Phaseolus vulgaris L.) is one of the most important grain legumes worldwide. Polyphenols are the predominant bioactive components with multifold bioactivities in diverse common bean cultivars. Phenolic acids, flavonoids, and proanthocyanidins are the main polyphenols in common beans, and colorful common beans are overall rich in polyphenols, mainly in their pigmented seed coats. In addition, factors of influence, such as genotype, environmental conditions, storage, and processing methods, play a critical role in the content and composition of common bean polyphenols. Besides, analytical methods, including extraction, separation, and identification, are of importance for precise and comparable evaluation of polyphenols in common beans. Therefore, in order to provide a comprehensive and updated understanding of polyphenols in common beans, this review first summarizes the content and different compositions of polyphenols in common beans, and next discusses the factors affecting these compositions, followed by introducing the analytical methods for common bean polyphenols, and finally highlights the antioxidant activity of polyphenols in common beans. Considering the recent surge in interest in the use of grain legumes, we hope this review will further stimulate work in this field by providing a blueprint for further analytical studies to better utilize common bean polyphenols in food products to improve human nutrition.

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“…In addition to its inhibitory effects on most known MMPs, the encoded TIMP proteins are capable of promoting cell proliferation in a variety of cell types and may also have anti‐apoptotic functions. Estrogen can upregulate the expression of TIMPs to downregulate the expression of MMPs, which reduces the degradation of collagen to protect the skin (Kassira et al, ; Nemitz et al, ).…”

Section: Effects On Collagenmentioning

confidence: 99%

Recent advances in the anti‐aging effects of phytoestrogens on collagen, water content, and oxidative stress

Liu

Yan

et al. 2019

Phytotherapy Research

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Skin undergoes degenerative changes as it ages, which include the loss of elasticity, reductions in the epidermal thickness and collagen content, elastic fiber degeneration, and increased wrinkling and dryness. Skin aging can be significantly delayed by the administration of estrogen. Estrogen deficiency following menopause results in atrophic skin changes and the acceleration of skin aging. Estrogen administration has positive effects on human skin by delaying or preventing skin aging manifestations, but the use of estrogen replacement is a risk factor for breast and uterine cancer. Phytoestrogens are a large family of plant‐derived molecules possessing various degrees of estrogen‐like activity; they exhibit agonist or antagonist estrogenic properties depending on the tissue. These molecules could be ideal candidates to combat skin aging and other detrimental effects of hypoestrogenism. In this paper, we review the effects of phytoestrogens on human skin and the mechanisms by which phytoestrogens can alleviate the changes due to aging.

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Bioactive soy isoflavones: extraction and purification procedures, potential dermal use and nanotechnology-based delivery systems

Cited by 36 publications

References 109 publications

Recent Patents Concerning the use of Nanotechnology-based Delivery Systems as Skin Penetration Enhancers

Recent Patents Concerning the use of Nanotechnology-based Delivery Systems as Skin Penetration Enhancers

Polyphenols in Common Beans (Phaseolus vulgaris L.): Chemistry, Analysis, and Factors Affecting Composition

Recent advances in the anti‐aging effects of phytoestrogens on collagen, water content, and oxidative stress

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