Bioactive properties of Sambucus nigra L. as a functional ingredient for food and pharmaceutical industry

Młynarczyk, Karolina; Walkowiak-Tomczak, Dorota; Łysiak, Grzegorz P.

doi:10.1016/j.jff.2017.11.025

Cited by 191 publications

(221 citation statements)

References 76 publications

Supporting

Mentioning

201

Contrasting

Unclassified

Order By: Relevance

“…This plant belongs to the family of Caprrifoliaceae and is mostly used in the treatment of common cold, HIV, HSV-1, influenza, urinary tract infection, edema and other rheumatic diseases [ 149 , 267 ]. It contains several active components extracted from the leaves, flower and fruit parts of the plant, such as flavonoids, lectins, anthocyanin, etc., which have been found to increase the immunity and inhibit the viral activity [ 150 , 152 , 153 , 154 ]. However, in case of the H1N1 influenza virus, this plant has shown great potential to block or impede the entry of the virus into the host cells [ 149 , 155 , 268 ].…”

Section: Other Medicinal Plants In Use Against Various Viral Infecmentioning

confidence: 99%

Plants-Derived Biomolecules as Potent Antiviral Phytomedicines: New Insights on Ethnobotanical Evidences against Coronaviruses

Siddiqui

Danciu

Ashraf

et al. 2020

Plants

View full text Add to dashboard Cite

SARS-CoV-2 infection (COVID-19) is in focus over all known human diseases, because it is destroying the world economy and social life, with increased mortality rate each day. To date, there is no specific medicine or vaccine available against this pandemic disease. However, the presence of medicinal plants and their bioactive molecules with antiviral properties might also be a successful strategy in order to develop therapeutic agents against SARS-CoV-2 infection. Thus, this review will summarize the available literature and other information/data sources related to antiviral medicinal plants, with possible ethnobotanical evidence in correlation with coronaviruses. The identification of novel antiviral compounds is of critical significance, and medicinal plant based natural compounds are a good source for such discoveries. In depth search and analysis revealed several medicinal plants with excellent efficacy against SARS-CoV-1 and MERS-CoV, which are well-known to act on ACE-2 receptor, 3CLpro and other viral protein targets. In this review, we have consolidated the data of several medicinal plants and their natural bioactive metabolites, which have promising antiviral activities against coronaviruses with detailed modes of action/mechanism. It is concluded that this review will be useful for researchers worldwide and highly recommended for the development of naturally safe and effective therapeutic drugs/agents against SARS-CoV-2 infection, which might be used in therapeutic protocols alone or in combination with chemically synthetized drugs.

show abstract

Section: Other Medicinal Plants In Use Against Various Viral Infecmentioning

confidence: 99%

Plants-Derived Biomolecules as Potent Antiviral Phytomedicines: New Insights on Ethnobotanical Evidences against Coronaviruses

Siddiqui

Danciu

Ashraf

et al. 2020

Plants

View full text Add to dashboard Cite

show abstract

“…The related body of literature indicates a strong correlation between diet and degenerative diseases, and due to this fact, the use of natural compounds as ingredients in food has become a major concern for food technologists [ 5 , 6 ]. Berries and fruits are the main sources of bioactive compounds with many applications in the food, pharmaceutical, nutraceutical and cosmetic industries [ 7 , 8 , 9 , 10 ]. These bioactive compounds are mainly polyphenols, and among them, anthocyanins which have proved to have high nutritional and potential health value [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Time-Dependent Degradation of Polyphenols from Thermally-Processed Berries and Their In Vitro Antiproliferative Effects against Melanoma

Diaconeasa

2018

Molecules

View full text Add to dashboard Cite

Polyphenols are natural occurring micronutrients that can protect plants from natural weathering and are also helpful to humans. These compounds are abundantly found in fruits or berries. Because of berry seasonal availability and also due to their rapid degradation, people have found multiple ways to preserve them. The most common options are freezing or making jams. Polyphenol stability, during processing is a continuous challenge for the food industry. There are also multiple published data providing that they are sensitive to light, pH or high temperature, vectors which are all present during jam preparation. In this context the aim of this study was to assess phytochemical composition and bioactive compounds degradation after jam preparation. We also monitored their degradation during storage time and their in vitro antiproliferative potential when tested on melanoma cells. The obtained results revealed that when processed and stored in time, the bioactive compounds from berries jams are degrading, but they still exert antioxidant and antiproliferative potential. Prior to LC-MS analysis, polyphenolic compounds were identified as: flavonoids (anthocyanins (ANT), flavonols (FLA)) and non-flavonoid (hydroxycinnamic acids (HCA) and hydroxybenzoic acids (HBA)). The most significant decrease was observed for HCA compared to other classes of compounds. This variation is expected due to differences in constituents and phenolic types among different analyzed berries.

show abstract

“…Nevertheless, the most important flavonol extracted form elderflower is quercetin-3-rutinoside that along with kaempferol-3-rutinoside and isorhamnetin-3-rutinoside represents more than 90% of the total flavonoids in most analyzed genotypes. Other classes of polyphenolic compounds found in the elderflower, besides flavonoids, are flavonols (catechin, epicatechin, procyanidin trimer), and n-hydroxycinnamic acids (neochlorogenic acid, cr yptochlorogenic acid, 3-5ferroylchinonic acid, dicyclohexylquinic acid, 1,5-di-formylquinic acid [6].…”

mentioning

confidence: 99%

Evaluation of the Nephroprotective Effect of Sambucus Nigra Total Extract in a Rat Experimental Model of Gentamicine Nephrotoxicity

Ungur¹,

Buzatu²,

Lăcătuş³

et al. 2019

Rev. Chim.

View full text Add to dashboard Cite

Elderflower contains flavonoles, the most important of them being quercetin. These molecules have an important antioxidant effect. The goal of our study was to evaluate which conservation technique of elderflower results the highest concentration of rutin and and phenolic compounds. Further we evaluated the protective effects of these extracts against nephrotoxicity induced by gentamicin in rats. Sambucus nigra extract demonstrates nephroprotective effects in gentamicin-induced renal toxicity, significantly improving outcome and evolution in rats.

show abstract

Bioactive properties of Sambucus nigra L. as a functional ingredient for food and pharmaceutical industry

Cited by 191 publications

References 76 publications

Plants-Derived Biomolecules as Potent Antiviral Phytomedicines: New Insights on Ethnobotanical Evidences against Coronaviruses

Plants-Derived Biomolecules as Potent Antiviral Phytomedicines: New Insights on Ethnobotanical Evidences against Coronaviruses

Time-Dependent Degradation of Polyphenols from Thermally-Processed Berries and Their In Vitro Antiproliferative Effects against Melanoma

Evaluation of the Nephroprotective Effect of Sambucus Nigra Total Extract in a Rat Experimental Model of Gentamicine Nephrotoxicity

Contact Info

Product

Resources

About