2006
DOI: 10.1590/s0103-50532006000700005
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Bioactive flavonoids and triterpenes from Terminalia fagifolia (Combretaceae)

Abstract: Da madeira e das cascas do caule de Terminalia fagifolia foram isolados dois 1,3-diarilpropanos, 1-(4'-hidróxi-2'-metóxifenil)-3-(3"-metóxi-4"-hidróxifenil)-propano e 1-(2'-hidróxi-4',6'dimetóxifenil)-3-(3"-metóxi-4"-hidróxifenil)-propano, sete flavanonas, naringenina, 5-hidróxi-4',7dimetóxiflavanona, sakuranetina, isosakuranetina, 7,4'-dimetóxiflavanona, 7-hidróxi-4'metóxiflavanona, 7-metóxi-4'-hidróxiflavanona, duas chalconas, 2',4'-diidroxi-4-metóxichalcona e 2'-4-diidroxi-4'-metóxichalcona, uma flavana, 7,… Show more

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Cited by 33 publications
(31 citation statements)
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“…Although galloyl esters of triterpenes have been isolated from a few Combretaceous and Fagaceous plants (Ponou et al, 2008;Garcez et al, 2006;Conrad et al, 1998;Romussi et al, 1993), isolation of HHDP esters has only been achieved from two Castanopsis species (Ageta et al, 1988, Chen et al, 1993, and the present study represents the third example from the same genus. The compositions of the triterpene HHDP esters of C. fissa are much simpler than those of the other two species examined, which contain complex mixtures of isomers, including those with oleanane and ursane type triterpene cores, and positional and configurational isomers of the esters (Ageta et al, 1988).…”
Section: Discussionmentioning
confidence: 74%
“…Although galloyl esters of triterpenes have been isolated from a few Combretaceous and Fagaceous plants (Ponou et al, 2008;Garcez et al, 2006;Conrad et al, 1998;Romussi et al, 1993), isolation of HHDP esters has only been achieved from two Castanopsis species (Ageta et al, 1988, Chen et al, 1993, and the present study represents the third example from the same genus. The compositions of the triterpene HHDP esters of C. fissa are much simpler than those of the other two species examined, which contain complex mixtures of isomers, including those with oleanane and ursane type triterpene cores, and positional and configurational isomers of the esters (Ageta et al, 1988).…”
Section: Discussionmentioning
confidence: 74%
“…O β-tocoferol (4) é inédito no gênero Terminalia e, com exceção do sitosterol (8), 5 todas as demais substâncias são inéditas em T. fagifolia. A identificação estrutural foi baseada na análise dos espectros de RMN 1 H e 13 C e comparação com dados da literatura, sendo a configuração absoluta da catequina determinada por dicroísmo circular.…”
Section: Identificação Dos Constituintes Químicos Isoladosunclassified
“…4 Estudos realizados com T. fagifolia demonstraram que o extrato etanólico das cascas apresenta atividades citotóxica e antioxidante, bem como a ocorrência de flavonoides (flavanonas, chalconas e flavanas), 1,3-diarilpropanos, triterpenos pentacíclicos glicosilados e não-glicosilados e um esteroide, o sitosterol. 5 O extrato etanólico das folhas apresenta forte potencial antioxidante no ensaio do DPPH. 6 Nos últimos anos, um grande interesse no estudo de antioxidantes tem ocorrido devido, principalmente, às descobertas sobre o efeito dos radicais livres no organismo.…”
Section: Introductionunclassified
“…Previous studies on the extracts of this plant have indicated antibacterial and antifungal properties, but their chemical compositions have not yet been determined. However, phytochemical studies of other species of the genus Terminalia have reported the presence of flavonoids, terpenoids and their glycosides derivatives, tannins, flavonones and chalcones [9][10][11][12][13][14][15][16][17][18]. Besides, in spite of the work done on Terminalia species, no investigation has been attempted yet on the enzyme inhibition properties of their extracts and constituents targeting Glucose-6-phosphate dehydrogenase, Carbonic anhydrase and Glutathione S-transferase.…”
Section: Introductionmentioning
confidence: 99%