Current Opinion in Lipidology volume 30, issue 3, P244-254 2019 DOI: 10.1097/mol.0000000000000597 View full text
Oscar Chávez-Talavera, Joel Haas, Guillaume Grzych, Anne Tailleux, Bart Staels

Abstract: Purpose of review: To discuss the influence of obesity, insulin resistance, type 2 diabetes (T2D) and non-alcoholic fatty liver disease (NAFLD) on bile acid (BA) metabolism and analyze whether these findings reinforce current beliefs about the role of BAs in the pathophysiology of these diseases. Recent findings: Discordant results on plasma BA alterations in NAFLD patients have been reported. Obesity, insulin resistance and T2D, common co-morbidities of NAFLD, have been associated with BA changes, but the ind…

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