Bilateral anterior segment dysgenesis with the presumed Peters’ anomaly in a cat

Abstract

A seven-month-old female domestic shorthaired cat was presented for buphthalmos in the right eye and corneal cloudiness in the left eye. Full ophthalmic examinations were performed for both eyes and enucleation was done for the right nonvisual eye. Congenital glaucoma caused by anterior segment dysgenesis was confirmed for the right eye. In the left eye, slit-lamp examination revealed focal corneal edema with several iris strands from iris collarette to the affected posterior corneal surfaces. Circular posterior corneal defect was suggested to be the cause of edema. Goniodysgenesis, additionally, was identified. Taken together, the diagnosis of Peters’ anomaly which is a subtype of anterior segment dysgenesis was suggested in the left eye.

Epidemiology and clinical presentation of feline presumed hereditary or breed-related ocular diseases in France: retrospective study of 129 cats

“…This is consistent with previous reports that described ASD mostly in DSHs. 24,32,33 Despite the over-representation of DSHs diagnosed with ASD in our study, we cannot conclude a predisposition of DSHs for this disease because of the vast heterogeneity of the DSH cats. Consistent with previous reports, no sex over-representation was observed in our study.…”

“…33 As ASD is a congenital ocular disease, it was not unexpected to find this abnormality mostly in young cats, with a median age of 8 months in our study, similar to previous reports. 24,32,34 Other ocular abnormalities were observed in our study (Tables 2 and 3) with a low prevalence, which prevented statistical analysis: microphthalmia, strabismus, palpebral dermoid, distichia, palpebral coloboma, apocrine hydrocystoma, corneal dystrophy, uveal cyst, primary lens luxation, microphakia, progressive retinal degeneration, optic nerve coloboma and primary glaucoma. Our results cannot confirm a possible breed predisposition for these ocular diseases; however, a breed or familial predisposition has been suspected for primary lens luxation in related DSHs.…”

“…33 As ASD is a congenital ocular disease, it was not unexpected to find this abnormality mostly in young cats, with a median age of 8 months in our study, similar to previous reports. 24,32,34…”

Ocular hamartoma in a five‐day‐old calf

“…In human and animals, lesions related to ASD include a wide variety of intraocular defects that impair vision 11 . ASD is rarely reported in cattle, 11 and complications from ASD result in enlargement of the affected eye 12, 13 . ASD results in an enlarged orbit due to an intraorbital deformity, whereas a hamartoma results in an abnormal eye mass, consisting of mature cells.…”