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“…There were no clinical evidence of thrombosis development in any of the organs for 3 years after the surgery. Therefore, acute adrenal insufficiency should be considered, particularly in bilateral adrenal hemorrhage (1,2,(16)(17)(18). In addition, unilateral adrenal hemorrhage could also lead to adrenal insufficiency (19).…”
Section: Discussionmentioning
confidence: 99%
“…There were no clinical evidence of thrombosis development in any of the organs for 3 years after the surgery. Therefore, acute adrenal insufficiency should be considered, particularly in bilateral adrenal hemorrhage (1,2,(16)(17)(18). In addition, unilateral adrenal hemorrhage could also lead to adrenal insufficiency (19).…”
Section: Discussionmentioning
confidence: 99%
“…Due to the hypermethylation of the DNA repair enzyme O6-methylguanine-DNA-methyltransferase (MGMT), the effect of TMZ is increased. In the case of aggressive pituitary adenomas and pituitary carcinomas, various studies suggest that the determination of MGMT protein expression has a predictive value for the response to temozolomide therapy [58]. Routine use as a predictive biomarker is currently still being discussed.…”
Section: Pituitary Carcinomamentioning
confidence: 99%