Bidirectional fear modulation by discrete anterior insular circuits in male mice
Sanggeon Park,
Yeowool Huh,
Jeansok J. Kim
et al.
Abstract:The brain's ability to appraise threats and execute appropriate defensive responses is essential for survival in a dynamic environment. Humans studies have implicated the anterior insular cortex (aIC) in subjective fear regulation and its abnormal activity in fear/anxiety disorders. However, the complex aIC connectivity patterns involved in regulating fear remain under investigated. To address this, we recorded single units in the aIC of freely moving mice that had previously undergone auditory fear conditioni… Show more
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