BHA study in pigs

Scientific evaluation of the safety factor for the acceptable daily intake (ADI). Case study: Butylated hydroxyanisole (BHA)

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Scientific evaluation of the safety factor for the acceptable daily intake (ADI). Case study: Butylated hydroxyanisole (BHA)

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Butylated Hydroxyanisole and Its Metabolitetert-Butylhydroquinone Differentially Regulate Mitogen-activated Protein Kinases

“…Thus, activation of ERK2 by BHA and tBHQ may actually enhance cell growth or survival. It is tempting to speculate that this growth-stimulating effect of ERK2 activation may also underlie the carcinogenic or tumor-promoting activities of BHA and tBHQ in some animal models of cancer (15,16). Unlike ERKs, JNKs may mediate more diverse cellular processes, depending on the stimuli.…”

Response of Growing Japanese Quails to Different Types of Some Medicinal Seed Oils as Enhancing Additives

“…The ingredients and chemical composition of the experimental basal diet are shown in Table (1). While, chemical composition of oil additives including experimental diets were determined by [13] are presented in Table (2). Also, the fatty acid content of the tested oils is presented in Tables (3-1) [14], (3-2) [15] and (3-3) [16].…”

Scientific evaluation of the safety factor for the acceptable daily intake (ADI). Case study: Butylated hydroxyanisole (BHA)

“……”

Butylated Hydroxyanisole and Its Metabolitetert-Butylhydroquinone Differentially Regulate Mitogen-activated Protein Kinases

“…Thus, activation of ERK2 by BHA and tBHQ may actually enhance cell growth or survival. It is tempting to speculate that this growth-stimulating effect of ERK2 activation may also underlie the carcinogenic or tumor-promoting activities of BHA and tBHQ in some animal models of cancer (15,16). Unlike ERKs, JNKs may mediate more diverse cellular processes, depending on the stimuli.…”

Response of Growing Japanese Quails to Different Types of Some Medicinal Seed Oils as Enhancing Additives

“…The ingredients and chemical composition of the experimental basal diet are shown in Table (1). While, chemical composition of oil additives including experimental diets were determined by [13] are presented in Table (2). Also, the fatty acid content of the tested oils is presented in Tables (3-1) [14], (3-2) [15] and (3-3) [16].…”

Scientific evaluation of the safety factor for the acceptable daily intake (ADI). Case study: Butylated hydroxyanisole (BHA)

“……”

Butylated Hydroxyanisole and Its Metabolitetert-Butylhydroquinone Differentially Regulate Mitogen-activated Protein Kinases

“…Thus, activation of ERK2 by BHA and tBHQ may actually enhance cell growth or survival. It is tempting to speculate that this growth-stimulating effect of ERK2 activation may also underlie the carcinogenic or tumor-promoting activities of BHA and tBHQ in some animal models of cancer (15,16). Unlike ERKs, JNKs may mediate more diverse cellular processes, depending on the stimuli.…”

Response of Growing Japanese Quails to Different Types of Some Medicinal Seed Oils as Enhancing Additives

“…The ingredients and chemical composition of the experimental basal diet are shown in Table (1). While, chemical composition of oil additives including experimental diets were determined by [13] are presented in Table (2). Also, the fatty acid content of the tested oils is presented in Tables (3-1) [14], (3-2) [15] and (3-3) [16].…”