1985
DOI: 10.1016/0278-6915(85)90206-6
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BHA isomers and hyperplasia

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“…In case of adverse or excessive oxidative stress the normal antioxidant defensesystem does not provide complete protection against free radicals and thereby external supply of antioxidants to be done to counter those free radicals 5 . But, the excessive use of synthetic antioxidants (BHA, BHT) leads to adverse toxic effects at higher doses 17 , which hinders their use in therapeutic applications. To overcome this dietary sources have been selected as antioxidants which are non-toxic and easily available.…”
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confidence: 99%