Beta2-agonists for acute bronchitis

Survey of potentially inappropriate prescriptions for common cold symptoms in Japan: A cross-sectional study

“…The rationale for classifying prescriptions containing β2-stimulants as potentially inappropriate is as follows: β2-stimulants are useful in patients with a history of cough, asthma, chronic obstructive pulmonary disease (COPD), and other diseases [ 27 ]. However, there is no clear benefit of these drugs for acute bronchitis and acute cough in adults, and side effects such as tremor and neurological symptoms may occur [ 28 ]. The tulobuterol patch, which was mainly used in this study, is approved for use only in Japan and Korea, and there is insufficient evidence in terms of its efficacy and safety [ 29 ].…”

Survey of potentially inappropriate prescriptions for common cold symptoms in Japan: A cross-sectional study

“…The rationale for classifying prescriptions containing β2-stimulants as potentially inappropriate is as follows: β2-stimulants are useful in patients with a history of cough, asthma, chronic obstructive pulmonary disease (COPD), and other diseases [ 27 ]. However, there is no clear benefit of these drugs for acute bronchitis and acute cough in adults, and side effects such as tremor and neurological symptoms may occur [ 28 ]. The tulobuterol patch, which was mainly used in this study, is approved for use only in Japan and Korea, and there is insufficient evidence in terms of its efficacy and safety [ 29 ].…”

Antibiotic treatment of acute bronchitis in smokers

“…Although β‐agonists are generally well‐tolerated, patients should be warned of common adverse effects, such as tremulousness, nervousness, or palpitations. 30 …”

Guidelines for the management of adult lower respiratory tract infections - Full version

“…One new updated Cochrane review on cough medication concluded that there is no clear benefit from interventions [237] Some of the studies in this review did report some beneficial effects from expectorants and antitusive agents, but these studies were small and suffered from methodological flaws. The Cochrane review on the use of bronchodilators in acute cough showed no beneficial effects [238]. One new RCT on the effects of inhaled fluticasone in patients with acute cough showed a small effect on symptom severity in the second week of disease.…”

“…[237]To assess the effects of oral over‐the‐counter cough preparations for acute cough.MA1A−Smucny et al. [238]To determine whether beta2‐agonists improve the symptoms of acute bronchitis in patients who do not have underlying pulmonary disease.MA1A+Ponsioen et al. [239]To investigate the short‐term effects of an inhaled steroid (fluticasone propionate (FP)) on coughRCT2A+…”

Survey of potentially inappropriate prescriptions for common cold symptoms in Japan: A cross-sectional study

“…The rationale for classifying prescriptions containing β2-stimulants as potentially inappropriate is as follows: β2-stimulants are useful in patients with a history of cough, asthma, chronic obstructive pulmonary disease (COPD), and other diseases [ 27 ]. However, there is no clear benefit of these drugs for acute bronchitis and acute cough in adults, and side effects such as tremor and neurological symptoms may occur [ 28 ]. The tulobuterol patch, which was mainly used in this study, is approved for use only in Japan and Korea, and there is insufficient evidence in terms of its efficacy and safety [ 29 ].…”

Antibiotic treatment of acute bronchitis in smokers

“…Although β‐agonists are generally well‐tolerated, patients should be warned of common adverse effects, such as tremulousness, nervousness, or palpitations. 30 …”

Guidelines for the management of adult lower respiratory tract infections - Full version

“…One new updated Cochrane review on cough medication concluded that there is no clear benefit from interventions [237] Some of the studies in this review did report some beneficial effects from expectorants and antitusive agents, but these studies were small and suffered from methodological flaws. The Cochrane review on the use of bronchodilators in acute cough showed no beneficial effects [238]. One new RCT on the effects of inhaled fluticasone in patients with acute cough showed a small effect on symptom severity in the second week of disease.…”

“…[237]To assess the effects of oral over‐the‐counter cough preparations for acute cough.MA1A−Smucny et al. [238]To determine whether beta2‐agonists improve the symptoms of acute bronchitis in patients who do not have underlying pulmonary disease.MA1A+Ponsioen et al. [239]To investigate the short‐term effects of an inhaled steroid (fluticasone propionate (FP)) on coughRCT2A+…”

Survey of potentially inappropriate prescriptions for common cold symptoms in Japan: A cross-sectional study

“…The rationale for classifying prescriptions containing β2-stimulants as potentially inappropriate is as follows: β2-stimulants are useful in patients with a history of cough, asthma, chronic obstructive pulmonary disease (COPD), and other diseases [ 27 ]. However, there is no clear benefit of these drugs for acute bronchitis and acute cough in adults, and side effects such as tremor and neurological symptoms may occur [ 28 ]. The tulobuterol patch, which was mainly used in this study, is approved for use only in Japan and Korea, and there is insufficient evidence in terms of its efficacy and safety [ 29 ].…”

Antibiotic treatment of acute bronchitis in smokers

“…Although β‐agonists are generally well‐tolerated, patients should be warned of common adverse effects, such as tremulousness, nervousness, or palpitations. 30 …”

Guidelines for the management of adult lower respiratory tract infections - Full version

“…One new updated Cochrane review on cough medication concluded that there is no clear benefit from interventions [237] Some of the studies in this review did report some beneficial effects from expectorants and antitusive agents, but these studies were small and suffered from methodological flaws. The Cochrane review on the use of bronchodilators in acute cough showed no beneficial effects [238]. One new RCT on the effects of inhaled fluticasone in patients with acute cough showed a small effect on symptom severity in the second week of disease.…”

“…[237]To assess the effects of oral over‐the‐counter cough preparations for acute cough.MA1A−Smucny et al. [238]To determine whether beta2‐agonists improve the symptoms of acute bronchitis in patients who do not have underlying pulmonary disease.MA1A+Ponsioen et al. [239]To investigate the short‐term effects of an inhaled steroid (fluticasone propionate (FP)) on coughRCT2A+…”