1983
DOI: 10.1001/archderm.119.3.222
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Benzoyl peroxide and epidermal wound healing

Abstract: The effectiveness of 10%, 20%, and 50% benzoyl peroxide in a lotion, 20% benzoyl peroxide in a gel, and the effect of the vehicles alone on wound reepithelialization were evaluated in young domestic pigs. Twenty percent benzoyl peroxide suspension in a lotion base substantially increased the rate of reepithelialization by 33% over a seven-day evaluation period. Twenty percent benzoyl peroxide suspension in a gel base and 10% benzoyl peroxide suspension in a lotion base slightly enhanced epidermal resurfacing, … Show more

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Cited by 8 publications
(6 citation statements)
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“…12 Furthermore, BPO has not been shown to adversely affect wound healing, and some evidence suggests potential benefit in this area. 2,5,16 Other centers have studied the effect of BPO on C acnes burden in patients undergoing shoulder surgery. Sabetta et al 14 reviewed 50 patients treated with 48 hours of 5% BPO before shoulder arthroscopy.…”
Section: Discussionmentioning
confidence: 99%
“…12 Furthermore, BPO has not been shown to adversely affect wound healing, and some evidence suggests potential benefit in this area. 2,5,16 Other centers have studied the effect of BPO on C acnes burden in patients undergoing shoulder surgery. Sabetta et al 14 reviewed 50 patients treated with 48 hours of 5% BPO before shoulder arthroscopy.…”
Section: Discussionmentioning
confidence: 99%
“…The first mention about the medical using of benzoyl peroxide dates back to 1929, where Lyon and Reynolds reported effective treatment of burns, wounds and varicose veins by benzoyl peroxide [ 200 ]. Subsequently it was found that it has antibacterial [ 201 , 202 ], anti-inflammatory [ 203 ], cheratolic [ 204 ], and wound-healing [ 205 , 206 ] effects. Presently, benzoyl peroxide is widely used agent for acne treatment because of its efficacy and good tolerability in patients [ 207 , 208 ].…”
Section: Acyclic Peroxidesmentioning
confidence: 99%
“…The role of various substances in wound healing has been rigorously investigated in animal models, searching for new and improved methods of wound management 1 . The effect of many topically applied agents such as scarlet red ointment, 2–8 benzoyl peroxide lotion, 9–15 bacitracin ointment, 15–17 silver sulfadiazine cream, 15–19 and aloe vera gel 20–24 on wound healing has been studied extensively. However, several new products have recently been introduced and new indications have been developed for existing products that could also significantly influence wound healing.…”
Section: Introductionmentioning
confidence: 99%