Benign Non-Nevoid Melanoepithelioma of the Skin (Bloch)

Traub, Eugene F.

doi:10.1001/archderm.1950.01530130143019

Cited by 9 publications

(2 citation statements)

References 14 publications

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“…First described by Bloch in 1926 as a Melanoepithelioma, Mishima & Pinkus in 1960 gave it clarity by introducing the term melanoacanthoma. The 17 cases reported in the literature to date attest to the rarity of this lesion which may test the acuity of both clinician and pathologist (Traub 1950, Spott et aL 1972, Reaves 1974, Delacr^taz, 1975.…”

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confidence: 99%

Melanoacanthoma

Ol¹,

Rowden²,

Tm³

et al. 1978

J Cutan Pathol

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Electronmicroscopic studies confirmed that melanoacanthoma is a non-nevoid elevated epithelial tumor composed of keratinocytes of both basaloid and spinous differentiation and of large dentritic melanocytes. The block in transfer of pigment from melanocytes to keratinocytes was found not to be complete. Langerhans cells, present in the malpighian layers were normal in morphology. Immunofluorescent studies and an immunoprecipitin assay also showed our patient's melanoacanthoma not to be related to malignant melanoma.

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confidence: 99%

Melanoacanthoma

Ol¹,

Rowden²,

Tm³

et al. 1978

J Cutan Pathol

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“…Melanoacanthoma has been described once previously on the eyelid, occurring in a 40‐year‐old black man as multiple, minute, individual and confluent, dark, shiny papules limited in distribution to the left upper eyelid 3 . Cutaneous melanoacanthoma is usually evident as a single, pigmented, verrucous, round or oval plaque with a diameter ranging from a few millimeters to 10 cm 4–14 . Cutaneous melanoacanthomas are mainly found on the head, particularly the lips, and the trunk.…”

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confidence: 99%

Giant cutaneous melanoacanthoma

et al. 2004

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A 45‐year‐old male cook was seen for the evaluation and removal of a “mole on my eye” of steady growth during the previous 6 months. The patient stated that he had had a “brown spot” above his left eye for 17 years prior to its recent enlargement; it was now partly blocking the vision in his left eye. He denied a history or family history of cutaneous tumors, including skin cancer. On examination, a 2.5‐cm × 0.5‐cm × 0.8‐cm, horn‐like, darkly pigmented, cutaneous nodule was evident extending from the left upper eyelid downwards to below the lower eyelid (Figs 1 and 2). He also had scattered, skin‐colored, 2–3‐mm cystic papules on his anterior mid‐chest. A shave excision specimen was obtained from the eyelid nodule. 1 Horn‐like, cutaneous nodule extending from the left upper eyelid downwards to below the lower eyelid 2 Close up, demonstrating the morphologic features to better advantage Microscopic examination demonstrated acanthosis, hyperkeratosis, and papillomatosis (Fig. 3). Large dendritic cells with abundant melanin granules were spread throughout the epidermis. In addition, small basaloid or spinous keratinocytes were present in the malpighian layer. 3 Histology of the nodule, showing an epidermis with acanthosis, hyperkeratosis, papillomatosis, and large dendritic cells with abundant melanin granules spread throughout the epidermis (hematoxylin and eosin; original magnification, × 100)

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Benign Mixed Tumor of Melanocytes and Malpighian Cells

Mishima¹,

Pinkus²

1960

Arch Dermatol

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Benign Non-Nevoid Melanoepithelioma of the Skin (Bloch)

Cited by 9 publications

References 14 publications

Melanoacanthoma

Melanoacanthoma

Giant cutaneous melanoacanthoma

Benign Mixed Tumor of Melanocytes and Malpighian Cells

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