1960
DOI: 10.1001/archderm.1960.03730040043009
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Benign Mixed Tumor of Melanocytes and Malpighian Cells

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Cited by 95 publications
(34 citation statements)
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“…In contrast in the intraepidermic epithelioma one cannot appreciate basaloid cells, the proliferation is limited to the nests which are also bigger and demonstrate a more disorderly cellular ar rangement. In our case a differential diagno sis with melanoacanthoma is also appro priate, given the cellular pigmentation ob served [24], In 1956, Smith and Coburn [22] described a lesion which they call hidroacanthoma simplex, in fact an intraepidermic poroma [25], a verrucous variant of which Cook and Ridgway [9] superpose to the intraepidermal epithelioma. Bowen's disease corresponds to an in situ malignancy and is characterized by a marked cellular polymorphism, occasion ally of basaloid typology, which confers a distinctive nature upon it, although it may show a clonal growth or may form Borsttype intraepidcrmic nests [11,13].…”
Section: Discussionmentioning
confidence: 55%
“…In contrast in the intraepidermic epithelioma one cannot appreciate basaloid cells, the proliferation is limited to the nests which are also bigger and demonstrate a more disorderly cellular ar rangement. In our case a differential diagno sis with melanoacanthoma is also appro priate, given the cellular pigmentation ob served [24], In 1956, Smith and Coburn [22] described a lesion which they call hidroacanthoma simplex, in fact an intraepidermic poroma [25], a verrucous variant of which Cook and Ridgway [9] superpose to the intraepidermal epithelioma. Bowen's disease corresponds to an in situ malignancy and is characterized by a marked cellular polymorphism, occasion ally of basaloid typology, which confers a distinctive nature upon it, although it may show a clonal growth or may form Borsttype intraepidcrmic nests [11,13].…”
Section: Discussionmentioning
confidence: 55%
“…Today these two entities are recognized as separate and distinct. It is defined as benign combined neoplasm of epidermal keratinocyte and large dendritic melanocytes [7]. However, the term "melanoacanthoma" was first used by Mishima and Pinkus in 1960 [13].…”
Section: Discussionmentioning
confidence: 99%
“…Mishima and Pinkus stated that cutaneous melanoacanthoma is a rare type of pigmented seborrheic keratosis which shows an increase in the concentration of melanocytes [7]. It should be differentiated from other types of pigmented seborrheic keratosis found in the head and neck region, or pigmented basal cell carcinoma.…”
Section: Introductionmentioning
confidence: 99%
“…En 1927, Bloch [2] décrivait, sous le nom de «bénignes, nicht naevoides Melanoepitheliom der Haut», deux types de tumeurs pigmentées: le premier type correspond à la tumeur appelée «melanoacanthoma» par Mishima et Pinkus [4] en I960, et dont 4 cas ont été publiés depuis lors [1,5,6]. Sur la base de 13 cas, Mishima et Pinkus [4] décrivent une tumeur caractérisée par une hyperplasie de l'épiderme et du derme papillaire, avec un aspect verruqueux ou papillomateux.…”
Section: Commentairesunclassified
“…Sur la base de 13 cas, Mishima et Pinkus [4] décrivent une tumeur caractérisée par une hyperplasie de l'épiderme et du derme papillaire, avec un aspect verruqueux ou papillomateux. Du point de vue cellulaire, le mélano-acanthome est formé de plages de cellules basaloïdes, petites et foncées, et de plages de cellules malpighiennes, plus grandes, avec tendance à la kératini sation centrale; en outre, la tumeur contient de nombreuses cellules dendri tiques, fortement dopa-positives, bourrées de mélanine; elles sont de plus grande taille que les mélanocytes normaux, comme gonflées par la mélanine qu'elles retiennent; elles ne la cèdent en effet que peu ou pas aux kératino cytes voisins.…”
Section: Commentairesunclassified