Benign Mixed Tumor of Melanocytes and Malpighian Cells

Oral melanoacanthoma with prominent spongiotic intraepithelial vesicles

“…However, a case of oral melanoacanthoma with spongiosis has been reported recently (7). Spongiosis, to our knowledge, has not been described in any cutaneous melanoacanthoma (2). We report an additional case of oral melanoacanthoma with severe spongiosis forming intraepithelial vesicles supporting clinical findings of other investigators that oral melanoacanthoma is not a neoplasm, but a mucositis.…”

Pathogenesis and clinicohistopathological caractheristics of melanoacanthoma: A systematic review

“…The relationship between melanocytes and keratinocytes is very similar to the realtion observed in the melanoacanthoma ( 23 ). This rare lesion was named Bort-Jadasshon intraepidermal epithelioma and it matches with the terms described by Bloch in 1927 and Mishima in 1960 when melanoacanthoma was called “non-cutaneous benign melanoepitelioma nevoid” ( 24 , 25 ).…”

Jadassohn’s Intraepidermal Epithelioma

“…In contrast in the intraepidermic epithelioma one cannot appreciate basaloid cells, the proliferation is limited to the nests which are also bigger and demonstrate a more disorderly cellular ar rangement. In our case a differential diagno sis with melanoacanthoma is also appro priate, given the cellular pigmentation ob served [24], In 1956, Smith and Coburn [22] described a lesion which they call hidroacanthoma simplex, in fact an intraepidermic poroma [25], a verrucous variant of which Cook and Ridgway [9] superpose to the intraepidermal epithelioma. Bowen's disease corresponds to an in situ malignancy and is characterized by a marked cellular polymorphism, occasion ally of basaloid typology, which confers a distinctive nature upon it, although it may show a clonal growth or may form Borsttype intraepidcrmic nests [11,13].…”