Benign Cystic Teratoma: An Uncommon Cause of Anterior Mediastinal Mass.

Verhaeghe, W; Meysman, Marc; Noppen, Marc; Monsieur, I; Lamote, Jan; Beeck, Bart Op de; Pierré, Erwin; W, Vincken

doi:10.1080/17843286.1995.11718434

Cited by 12 publications

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“…The appearance of the mass on the CT‐scan and the absence of tumor cells in the BAL fluid sample changed our diagnostic suspicion from lymphoma, a systemic tumor, to a localized mediastinal tumor subsequently confirmed by histological examination of the biopsy specimens taken from the mass. A mature teratoma is a benign slow‐growing neoplasm, accounting for 8–13% of all mediastinal tumors, which represents the most frequent germ cell tumor derived from all three germinal layers (ectodermal, mesodermal, and endodermal) 7, 8. Whereas, our patient's tumor was diagnosed when he was 12 years old, the diagnosis is usually made in adolescents, and always by chance.…”

Section: Discussionmentioning

confidence: 99%

The peri‐PCI enzyme rise: Speed bump or springboard to disaster?

Blankenship

2008

Cathet Cardio Intervent

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Section: Discussionmentioning

confidence: 99%

The peri‐PCI enzyme rise: Speed bump or springboard to disaster?

Blankenship

2008

Cathet Cardio Intervent

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“…[8] Adherent mediastinal pleura and pericardium can be dealt with by removal of the involved portions as was done in this case. As most mediastinal teratomas are benign, even a subtotal resection conserving adherent vital structures provides excellent results.…”

Section: Discussionmentioning

confidence: 99%

Fever of unknown origin: A case of post obstructive pneumonia complicating mature teratoma

Bhatt

Nandan

Sen

et al. 2013

Ann Med Health Sci Res

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Mediastinal teratomas are rare germ cell tumors in children accounting for only 4.3% of all germ cell tumours. Here, we describe a three year old child who was misdiagnosed as a case of pulmonary tuberculosis at periphery despite of his chest X ray showing large homogenous opacification of left hemithorax with areas of calcifications and subsequently diagnosed as a case of benign mature teratoma with post obstructive pneumonia. Our case highlights the need for careful evaluation of chest X-ray (CXR) by the treating physicians, especially when CXR had a large homogenous opacity with shifting of mediastinum and presence of a few calcified shadows, which may clinch a rare diagnosis of an uncommon disorder.

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“…Mediastinal teratomas are rare neoplasms in children and comprise 8-13% of all mediastinal tumors. 1 The anterosuperior mediastinum is the most common location of these tumors, although they can also be seen in the posterior mediastinum with an incidence of 3-8%. 2 …”

Section: Introductionmentioning

confidence: 99%

Benign Mature Cystic Teratoma of the Anterior Mediastinum Leading to Heart Failure: Report of a Case

et al. 2003

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of cough, dyspnea, fever, palpitation, and dizziness which had started 6-7 months before admission and thereafter gradually worsened. On physical examination a gallop rhythm and a 2/6 systolodiastolic murmur was heard, and the patient was also found to be orthopneic. A chest X-ray showed a large shadow in the cardiac region and mediastinal enlargement. Echocardiography revealed a cystic, extrapericardial, anterior mediastinally located mass which was compressing all the cavities of the heart with an increased pericardial effusion at the apex. Computed tomography (CT) and magnetic resonance imaging (MRI) examinations of the chest showed a cystic, lobulated, extrapericardial anterior mediastinally located mass with a small calcification focus (Fig. 1). The outcome of a bone marrow aspirate examination was normal and no atypical cells were found.The mass was surgically treated since it was suspected to be a thymic cyst. The mass was completely removed from the anterior mediastinum (Fig. 2). During the operation a 13 ϫ 10 ϫ 8-cm sized tumor was found to severely adhere to the anterior part of the pericardium, and the left and right mediastinal pleuras, while also compressing the heart. The tumor hung down from the upper part of the thymus and was involved with the pericardial part of the left phrenic nerve. It was therefore removed from the pericardium and dissected from the left phrenic nerve. A histopathological examination of the tumor disclosed a benign mature cystic teratoma consisting of pancreatic tissue, smooth muscle, salivary gland tissue, sebaceous glands, connective tissue, and mixoid connective tissue with hemorrhaging and areas of mononuclear cell infiltration (Fig. 3).The postoperative course was uneventful and a control chest X-ray was normal without any significant elevation of the left diaphragm. The patient was discharged on the seventh postoperative day. At the 1 year follow-up he is still healthy without any recurrence. AbstractA 12-year-old male child was referred to our clinic for the surgical treatment of an anterior mediastinal mass, suspected to be a thymic cyst, which was considered to potentially lead to cardiac failure. The mass was resected completely with a median sternotomy. The postoperative course was uneventful. A pathological examination revealed a mature cystic teratoma of anterior mediastinum which is a very rare cystic tumor at this location. The incidence, diagnostic procedures, complications, and treatment of mediastinal teratomas are discussed along with a review of the literature.

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Benign Cystic Teratoma: An Uncommon Cause of Anterior Mediastinal Mass.

Cited by 12 publications

References 0 publications

The peri‐PCI enzyme rise: Speed bump or springboard to disaster?

The peri‐PCI enzyme rise: Speed bump or springboard to disaster?

Fever of unknown origin: A case of post obstructive pneumonia complicating mature teratoma

Benign Mature Cystic Teratoma of the Anterior Mediastinum Leading to Heart Failure: Report of a Case

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