Benign angiofollicular lymph node hyperplasia (Castleman's disease) presenting as a solitary cervical mass

Castleman's disease and lymphoepithelial cysts of the parotid in childhood

“…Angiofollicular lymph node hyperplasia, or Castleman's disease, is a peculiar type of lymph node hyperplasia 1;2 that has so far been reported, including the present case, in only 45 patients younger than 13 years [3][4][5][6][7][8] . Two histological types are recognized: the classic hyalinevascular type, usually unicentric, and the plasma cell type, which can be multifocal and associated with systemic symptoms 1 .…”

Castleman's disease and lymphoepithelial cysts of the parotid in childhood

“…Angiofollicular lymph node hyperplasia, or Castleman's disease, is a peculiar type of lymph node hyperplasia 1;2 that has so far been reported, including the present case, in only 45 patients younger than 13 years [3][4][5][6][7][8] . Two histological types are recognized: the classic hyalinevascular type, usually unicentric, and the plasma cell type, which can be multifocal and associated with systemic symptoms 1 .…”

Castleman’s Disease: An Unusual Cause of a Neck Mass

“…Among the ves sels is a variable mixture of cells, predominantly lympho cytes which are arranged in 'onion-skin' layers around the follicle centres [1,8,11,12], The plasma cell variant is characterized by normal to large follicle centres, the pres ence of sheets of mature plasma cells and somewhat less vascular stroma [1,8,11,12], A third mixed variant sug gesting a transformation of plasma cell into hyaline vascu lar type has also been described [12],…”

Castleman's disease presenting within the cheek of a child

“…There is intrafollicular capillary proliferation and hyalinisation 3 . This variant is usually asymptomatic, unless the lesion causes indirect symptoms by compression of adjacent structures 12 .…”

Castleman's disease and lymphoepithelial cysts of the parotid in childhood

“…Angiofollicular lymph node hyperplasia, or Castleman's disease, is a peculiar type of lymph node hyperplasia 1;2 that has so far been reported, including the present case, in only 45 patients younger than 13 years [3][4][5][6][7][8] . Two histological types are recognized: the classic hyalinevascular type, usually unicentric, and the plasma cell type, which can be multifocal and associated with systemic symptoms 1 .…”

Castleman’s Disease: An Unusual Cause of a Neck Mass

“…Among the ves sels is a variable mixture of cells, predominantly lympho cytes which are arranged in 'onion-skin' layers around the follicle centres [1,8,11,12], The plasma cell variant is characterized by normal to large follicle centres, the pres ence of sheets of mature plasma cells and somewhat less vascular stroma [1,8,11,12], A third mixed variant sug gesting a transformation of plasma cell into hyaline vascu lar type has also been described [12],…”

Castleman's disease presenting within the cheek of a child

“…There is intrafollicular capillary proliferation and hyalinisation 3 . This variant is usually asymptomatic, unless the lesion causes indirect symptoms by compression of adjacent structures 12 .…”

Castleman's disease and lymphoepithelial cysts of the parotid in childhood

“…Angiofollicular lymph node hyperplasia, or Castleman's disease, is a peculiar type of lymph node hyperplasia 1;2 that has so far been reported, including the present case, in only 45 patients younger than 13 years [3][4][5][6][7][8] . Two histological types are recognized: the classic hyalinevascular type, usually unicentric, and the plasma cell type, which can be multifocal and associated with systemic symptoms 1 .…”

Castleman’s Disease: An Unusual Cause of a Neck Mass

“…Among the ves sels is a variable mixture of cells, predominantly lympho cytes which are arranged in 'onion-skin' layers around the follicle centres [1,8,11,12], The plasma cell variant is characterized by normal to large follicle centres, the pres ence of sheets of mature plasma cells and somewhat less vascular stroma [1,8,11,12], A third mixed variant sug gesting a transformation of plasma cell into hyaline vascu lar type has also been described [12],…”

Castleman's disease presenting within the cheek of a child

“…There is intrafollicular capillary proliferation and hyalinisation 3 . This variant is usually asymptomatic, unless the lesion causes indirect symptoms by compression of adjacent structures 12 .…”