Benign Acute Childhood Myositis

Sönmez, Fatma Müjgan; Çakır, Murat; Yayla, Şeker; Boz, Cavit

doi:10.1159/000078323

Cited by 15 publications

(7 citation statements)

References 8 publications

(29 reference statements)

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“…Symptoms of influenza complications linked to the musculature vary widely, from simple muscle pain to rhabdomyolysis. 6 7 9) IAM causes acute pain and muscular spasms during the recovery phase of the influenza infection, after the onset of respiratory symptoms. The IAM symptoms usually resolve within 3–10 days, and IAM thus has a good overall prognosis.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, deep venous thrombosis is exceedingly rare in otherwise healthy children, and usually involves only one extremity; it can be confirmed by a Doppler sonography and D-dimer level estimation in the blood. 6) …”

Section: Discussionmentioning

confidence: 99%

“…In cases where rhabdomyolysis is suspected, inpatient monitoring is indicated for early identification and treatment of associated complications such as acute renal failure, electrolyte imbalance, and compartment syndrome. 6) …”

Section: Discussionmentioning

confidence: 99%

“…IAM is a generally benign, self-limiting condition that usually affects boys and manifests as calf tenderness, and sudden onset of difficulty in walking after an influenza infection. 6) However, IAM may not be easily distinguishable from other diseases, and therefore, children may undergo unnecessary diagnostic testing and treatment. In addition, several IAM cases with a severe course and life-threatening complications have been also reported.…”

Section: Introductionmentioning

confidence: 99%

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Analysis of Clinical Manifestations and Laboratory Findings in Children with Influenza B-Associated Myositis: A Single Center Study

et al. 2018

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BackgroundInfluenza-associated myositis (IAM) is a rare and poorly recognized complication of influenza infection in children, and is characterized by acute onset of severe pain in the lower extremities and a refusal to ambulate walk. We sought to understand the association between IAM and influenza B infection and to investigate its clinical and laboratory characteristics in affected children.MethodsInfluenza B-associated myositis (IBAM) cases diagnosed in the pediatrics department of Wonkwang University Hospital from January 2010 and March 2016 were analyzed retrospectively.ResultsMedical records of affected children were examined, and clinical characteristics and laboratory findings were recorded. Of the 536 children diagnosed with influenza B infection, 47 children complained of bilateral calf pain with or without gait disturbance. All children exhibited elevated serum aspartate aminotransferase (AST) level. The median serum creatine kinase (CK) and lactate dehydrogenase (LDH) levels, reportedly elevated in myositis, were 2,597 IU/L and 678 IU/L, respectively. While the immunofluorescence test results were negative for some patients, the polymerase chain reaction test results indicated influenza B infection in all 47 children. At the time of hospital discharge, the patients' symptoms had resolved, and their CK levels had improved.ConclusionIBAM was generally benign and short, and although the blood AST, CK, and LDH levels were markedly high, the erythrocyte sedimentation rate and C-reactive protein levels were normal. Further, the duration of IBAM symptoms correlated with the duration of fever. The IBAM-associated clinical and laboratory findings are highly characteristic and may allow its rapid diagnosis during the influenza season.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Analysis of Clinical Manifestations and Laboratory Findings in Children with Influenza B-Associated Myositis: A Single Center Study

et al. 2018

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“…4 BACM usually follows the initial phase of an acute upper respiratory tract illness, most frequently associated with influenza viruses. 2 Several diagnostic investigations 3–7 are commonly performed when a child with the clinical picture of BACM is presented in order to distinguish this syndrome among other, more severe, pathological conditions. 4,7…”

Section: Introductionmentioning

confidence: 99%

Unnecessary diagnostic investigations in benign acute childhood myositis: a case series report

et al. 2012

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Benign acute childhood myositis (BACM) is a rare, acute, self-limiting muscle disorder, mainly affecting school-aged boys, with an excellent prognosis, requiring no therapeutic intervention. We report a series of seven previously healthy school-aged children with clinical and laboratory findings suggesting BACM where no specific diagnostic investigations were performed. All of the children were hospitalized without any specific therapeutic intervention and were discharged after two or three days free of symptoms, residual impairment or other complication. This report emphasizes that the correct diagnosis of BACM, by considering the characteristic clinical and laboratory findings of this syndrome and by recognizing more severe pathological conditions, which must be excluded from the diagnosis, can prevent unnecessary diagnostic investigations and reassure both parents and patients of the excellent prognosis.

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