2020
DOI: 10.1016/j.jff.2019.103692
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Beneficial effects of pomegranate peel extract on plasma lipid profile, fatty acids levels and blood pressure in patients with diabetes mellitus type-2: A randomized, double-blind, placebo-controlled study

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Cited by 54 publications
(81 citation statements)
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“…3 ) [ 244 , 263 , 264 ], anti-healing properties [ 265 ], anti-inflammatory, anti-infectious, anti-mutagenic and hepatoprotective properties [ [266] , [267] , [268] ]. PPW extract has beneficial effects on plasma lipid profile, fatty acid levels and blood pressure for patients with type-2 diabetes [ 36 ]. PPW enriched films have shown greater antioxidant activity and antibacterial capacity than the control film based on bean protein [ 269 ].…”
Section: Tpw Ppw and Bpw Valorisation Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…3 ) [ 244 , 263 , 264 ], anti-healing properties [ 265 ], anti-inflammatory, anti-infectious, anti-mutagenic and hepatoprotective properties [ [266] , [267] , [268] ]. PPW extract has beneficial effects on plasma lipid profile, fatty acid levels and blood pressure for patients with type-2 diabetes [ 36 ]. PPW enriched films have shown greater antioxidant activity and antibacterial capacity than the control film based on bean protein [ 269 ].…”
Section: Tpw Ppw and Bpw Valorisation Methodsmentioning
confidence: 99%
“…TPW, PPW and BPW may be used directly or after treatments as animal feed [ 15 , 16 ], soil amendment [ [17] , [18] , [19] ], bio-adsorbents [ 20 , 21 ], and the production of the outputs was obtained by the biorefinery process (biogas, bioethanol and biohydrogen) [ [22] , [23] , [24] , [25] , [26] ]. Numerous other studies have focused on the valorisation of TPW, PPW and BPW for the production of value-added products (essential oil, enzymes, food, medical and cosmetic products) [ [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , [36] , [37] ].…”
Section: Introductionmentioning
confidence: 99%
“…A 30 day supplementation with pomegranate extracts in individuals with overweight and obesity beneficially affected body weight, serum glucose, insulin, triglyceride, total cholesterol, LDL-C, HDL-C (high-density lipoprotein-cholesterol) and LDL-C to HDL-C proportion, while also acting as an anti-inflammatory agent, lowering inflammatory and lipid peroxidation biomarkers [91]. An eight week supplementation with pomegranate peel extracts attenuated the systolic and diastolic blood pressure in patients with type 2 diabetes and also presented hypolipemic, hypoglycemic, and antioxidative potential [92]. Finally, clinical studies with pomegranate seed oil in type 2 diabetic patients have resulted in reductions in the levels of fasting blood sugar, interleukin-6 and TNF-α (tumor necrosis factor-α); however, no significant changes have been observed in insulin and lipid profiles [93,94].…”
Section: Human Studiesmentioning
confidence: 99%
“…One of those is pomegranate ( Punica granatum L. , Punicaceae family) which is a well-known fruit consumed worldwide. Pomegranate has been traditionally used in the folk medicine due to its beneficial health properties and treatment of different chronic diseases like diabetes type 2 [ 16 , 17 ], atherosclerosis [ 18 , 19 ], cardiovascular diseases [ 20 ], inflammatory diseases [ 21 ] or cancer [ 22 ]. Pomegranate peel extracts are particularly rich with phytobiotics such as hydrolysable tannins (ellagitannin, punicalagin, punicalin, gallic and ellagic acid), flavonoids, anthocyanins and other phenols.…”
Section: Introductionmentioning
confidence: 99%
“…Pomegranate peel extracts are particularly rich with phytobiotics such as hydrolysable tannins (ellagitannin, punicalagin, punicalin, gallic and ellagic acid), flavonoids, anthocyanins and other phenols. These polyphenols possess a wide range of biologic properties including anti-inflammatory, antioxidant, hypoglycemic, lipid-lowering, antihypertensive or antimicrobial effects [ 17 , 23 , 24 ].…”
Section: Introductionmentioning
confidence: 99%