Bed-wetting and Its Association With Developmental Milestones in Early Childhood

Abstract

These findings show an association between bed-wetting and developmental milestones in early childhood. This study supports that bed-wetting could be indicative of a possible delay in the development of the central nervous system and could act as a noticeable indicator for parents and pediatricians.

Nocturnal enuresis in early adolescence and neurodevelopmental delay in infancy: a population-based study

“…The results of the present study are in agreement with those of previous epidemiological studies which targeted younger age groups or used single-point measures for neurodevelopmental delays [3,17,18,[25][26][27]. Regarding the prevalence and sex differences in NE, our research found a 9.2% prevalence at age 10 years, and boys were 2.7-fold more likely than girls to experience NE.…”

“…These results are consistent with a representative population-based study conducted in the UK (the ALSPAC study) [3]. As for the association between developmental delay and frequent NE, a Canadian population-based cohort study by Touchette et al revealed that relative to those that did not, children still NE at 4.5 years of age exhibited delayed motor development at 5 months in boys and delayed verbal development at 17 months in girls [27]. Using the ALSPAC samples, Sullivan et al reported that developmental delay in gross/ ne motor and communication/social skills in 1.5-year-olds predicted an increased risk of NE up to the age of 9 years [25].…”

Nocturnal enuresis in early adolescence and neurodevelopmental delay in infancy: A population‐based study

“…The results of the present study are in agreement with those of previous epidemiological studies that targeted younger age groups or used single‐point measures for neurodevelopmental delays 3,17,18,25–27 . Regarding the prevalence and sex differences in NE, our research found a 9.2% prevalence at age 10 years, and boys were 2.7‐fold more likely than girls to experience NE.…”

Association between the frequency of bedwetting and late preterm birth in children aged ≥5 years

“…However, in this study, among patients with NE, 41 out of 544 (7.5%) were born prematurely, and 77 (14.2%) of 544 were born with a low BW. These demographic data show similar prevalence rates to those previously reported . Taken together, it can be considered to show a general tendency in the proportion of enuresis patients who were born prematurely.…”