Becker's nevus associated with limb asymmetry

Becker Naevus Syndrome of the Lower Body: One Case and Review of the Literature

“…Less often, the naevus was located at the lower part of the body. Lucky et al were the first to describe a patient with BNS affecting the lower limbs in 1981 (71). Including our report, 10 cases of BNS affecting parts of the body below the waistline have been reported in English language publications so far (Table II).…”

“…It is noteworthy that discrimination between fatty tissue and muscle hypoplasia has been made in only a minority of cases. Items of hyperplasia included soft tissue swelling of the ipsilateral hand (70), hyperplasia of the ipsilateral lower limb (72), and enlargement of the ipsilateral foot (71). In the case presented by us, hypertrophy of the subcutaneous fat of the gluteal area ipsilateral to the naevus was noted.…”

Becker nevus syndrome

“…Shortness of the ipsilateral arm was reported by Copeman and Jones [1965], Moore and Schosser [1985], Glinick et al [1983], as well as by Glinick and Alper [1986]. Asymmetry of limbs was also noted by Lucky et al [1981] and Blanc et al [1988]. They described this as an enlargement of the ipsilateral limb but it cannot be excluded that in fact the asymmetry was caused by hypoplasia of the contralateral limb.…”

Acneiform lesions in Becker's nevus and breast hypoplasia

“…Skeletal anomalies, such as spina bifida, limb asymmetry, pectus excavatum, herniated disk, and vertebral scoliosis, have been reported 1,4,12 . Other associated abnormalities include accessory scrotum, congenital adrenal hyperplasia and supernumerary nipples, aplasia of the ipsilateral pectoralis major muscle, and localized lipoatrophy 6,13–16 …”

“…All these abnormalities suggest that Becker's nevus may represent an organoid nevus and may form part of the spectrum of epidermal nevi and the epidermal nevus syndrome 4,12 . The term “pigmented hairy epidermal nevus syndrome” has been proposed to describe the association of Becker's nevus with such noncutaneous abnormalities 19 …”