Abstract:In our previous study, we have found that
(BAY 41-2272), a guanylate cyclase agonist, activates human monocytes and the THP-1
cell line to produce the superoxide anion, increasing in vitro microbicidal activity,
suggesting that this drug can be used to modulate immune functioning in primary
immunodeficiency patients. In the present work, we investigated the potential of the
in vivo administration of BAY 41-2272 for the tr… Show more
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