Basal Cell Carcinoma in a Vaccination Scar

Foreign body reaction involving a Mantoux test site

“…Basal cell carcinoma has been reported to have developed at immunization sites 5–7 . However, unlike our case, scar tissue had formed at these sites before the development of the basal cell carcinoma.…”

Basal Cell Carcinoma Arising from Surgical Scars: A Case and Review of the Literature

“…There is no exact answer to the question of how trauma or resulting scar tissue plays a role in BCC pathogenesis, although some suggestions are presented for squamous cell carcinoma. 7 It has been pointed out that continuous irritation is a predisposing factor. Tight or thickened scars, especially over joints, become ulcerated.…”

“…The absence of any report dealing with BCC on the mons pubis is interesting because that area is susceptible to the chronic irritation of underwear and trauma has been suggested as an etiologic factor of BCC by some authors. 7,23,28 In this situation, it is thought that the surgical scar may have contributed to the growth of BCC on mons pubis, an area not exposed to the sun. It seems improbable that lacking immunologic mechanisms would create an environment interfering with immune surveillance.…”

Basal Cell Carcinoma Arising in a Cleft Lip Repair Scar

“…The potential role of trauma as an etiologic factor leading to BCC has been suggested in individual case reports 3,4 . Trauma encompasses thermal burns, vaccination sites, preexisting skin disease, sharp or blunt physical injury, and surgical scars 5 . In the 19th century, Marjolin 6 first associated trauma with carcinoma formation.…”

“…Six other cases of BCC in surgical scars have been reported in the literature 5 . The first of the BCC cases in a surgical scar occurred in a hair transplantation recipient site 5 years after the operation 9 .…”