Barrett’s esophagus patients are becoming younger: analysis of a large United States dataset

Yamasaki, Takahisa; Sakiani, Sasan; Maradey–Romero, Carla; Mehta, Rohini; Sandhu, Dalbir S.; Ganocy, Stephen J.; Hemond, Colin; Eisa, Mohamed; Fass, Ronnie

doi:10.1007/s10388-019-00707-7

Cited by 7 publications

(4 citation statements)

References 22 publications

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“…By contrast, intakes of leafy vegetables and fruit were inversely associated with risk of BE, as were dietary fiber and carotenoids [160]. The results of these studies underscore the concept that public health and clinical guidelines that incorporate dietary recommendations could reduce the risk of BE and, thereby, esophageal adenocarcinoma [160][161][162][163][164][165][166][167][168].…”

Section: Screening and Assessmentmentioning

confidence: 84%

Dietary and Nutritional Support in Gastrointestinal Diseases of the Upper Gastrointestinal Tract (I): Esophagus

Montoro

2022

Nutrients

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The esophagus is the centerpiece of the digestive system of individuals and plays an essential role in transporting swallowed nutrients to the stomach. Diseases of the esophagus can alter this mechanism either by causing anatomical damage that obstructs the lumen of the organ (e.g., peptic, or eosinophilic stricture) or by generating severe motility disorders that impair the progression of the alimentary bolus (e.g., severe dysphagia of neurological origin or achalasia). In all cases, nutrient assimilation may be compromised. In some cases (e.g., ingestion of corrosive agents), a hypercatabolic state is generated, which increases resting energy expenditure. This manuscript reviews current clinical guidelines on the dietary and nutritional management of esophageal disorders such as severe oropharyngeal dysphagia, achalasia, eosinophilic esophagitis, lesions by caustics, and gastroesophageal reflux disease and its complications (Barrett’s esophagus and adenocarcinoma). The importance of nutritional support in improving outcomes is also highlighted.

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Section: Screening and Assessmentmentioning

confidence: 84%

Dietary and Nutritional Support in Gastrointestinal Diseases of the Upper Gastrointestinal Tract (I): Esophagus

Montoro

2022

Nutrients

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“…A number of lifestyle changes or new eating trends lead to the diagnosis of pathological changes in the esophagus in younger and younger people. The increase in the trend is particularly visible over the last few years [13]. Concerning infants, it was discovered that GERD has an effect on ALTEs (apparent life-threatening events in infancy), while anti-reflux therapy considerably decreases the number of ALTE episodes [14].…”

Section: Reflux Diseases Of the Upper Gastrointestinal Tractmentioning

confidence: 99%

Application of Wavelet Transform and Fractal Analysis for Esophageal pH-Metry to Determine a New Method to Diagnose Gastroesophageal Reflux Disease

et al. 2022

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In this paper, a new method for analysing gastroesophageal reflux disease (GERD) is shown. This novel method uses wavelet transform (WT) and wavelet-based fractal analysis (WBFA) on esophageal pH-metry measurements. The esophageal pH-metry is an important diagnostic tool supporting the physician’s work in diagnosing some forms of reflux diseases. Interpreting the results of 24-h pH-metry monitoring is time-consuming, and the conclusions of such an analysis can sometimes be too subjective. There is no strict procedure or reference values to follow when the impedance measurements are assessed. Therefore, an attempt was made to develop a point of reference for the assessment process, helping to distinguish healthy patients from GERD patients. In this approach, wavelet transform (WT) and wavelet-based fractal analysis (WBFA) were used to aid the diagnostic process. With this approach, it was possible to develop two efficient computer methods to classify healthy and sick patients based on the pH measurement data alone. The WT method provided a sensitivity value of 93.33%, with 75% specificity. The results of the fractal analysis confirmed that the tested signals have features that enable their automatic classification and assignment to a group of sick or healthy people. The article will be interesting for those studying the application of wavelet and fractal analysis in biomedical waveforms. The authors included in the work a description of the implementation of the fractal and wavelet analysis, the descriptions of the results of the analyses, and the conclusions drawn from them. The work will also be of interest to those who study the methods of using machine learning and artificial intelligence in computer-aided, automatic medical diagnostics.

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“…GERD is a disease whose treatment requires substantial medical resources [16], and its risk factors include smoking, obesity, alcohol consumption, nonsteroidal anti-inflammatory drugs (NSAIDs), social factors, psychosomatic diseases, and genetic factors [17][18][19][20][21]. Meanwhile, there are also correlation between GERD and ethnicity, Helicobacter pylori infection, gender, age, and lifestyle [22][23][24][25]. A study reported that the prevalence of GERD varies greatly in different countries and regions, and its clinical characteristics, etiology, and pathogenesis factors vary [26].…”

Section: Epidemiology Of Gerdmentioning

confidence: 99%

Current Advancement on the Dynamic Mechanism of Gastroesophageal Reflux Disease

Zheng¹,

Yu²,

Wang³

et al. 2021

Int. J. Biol. Sci.

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Gastroesophageal reflux disease (GERD) is a common clinical disease associated with upper gastrointestinal motility disorders. Recently, with improvements in living standards and changes in lifestyle and dietary habits, the incidence of GERD has been increasing yearly. However, the mechanism of GERD has not been fully elucidated due to its complex pathogenesis, and this had led to unsatisfactory therapeutic outcomes. Currently, the occurrence and development of GERD involve multiple factors. Its pathogenesis is mainly thought to be related to factors, such as lower esophageal sphincter pressure, transient lower esophageal sphincter relaxation, crural diaphragmatic dysfunction, hiatus hernia, and impaired esophageal clearance. Therefore, explaining the pathogenesis of GERD more clearly and systematically, exploring potential and effective therapeutic targets, and choosing the best treatment methods have gradually become the focus of scholars' attention. Herein, we reviewed current advancements in the dynamic mechanism of GERD to better counsel patients on possible treatment options.

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Barrett’s esophagus patients are becoming younger: analysis of a large United States dataset

Cited by 7 publications

References 22 publications

Dietary and Nutritional Support in Gastrointestinal Diseases of the Upper Gastrointestinal Tract (I): Esophagus

Dietary and Nutritional Support in Gastrointestinal Diseases of the Upper Gastrointestinal Tract (I): Esophagus

Application of Wavelet Transform and Fractal Analysis for Esophageal pH-Metry to Determine a New Method to Diagnose Gastroesophageal Reflux Disease

Current Advancement on the Dynamic Mechanism of Gastroesophageal Reflux Disease

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