Balanced bidirectional optogenetics reveals the causal impact of cortical temporal dynamics in sensory perception
Daniel Quintana,
Hayley Bounds,
Julia Veit
et al.
Abstract:Whether the fast temporal dynamics of neural activity in brain circuits causally drive perception and cognition remains one of most longstanding unresolved questions in neuroscience1–6. While some theories posit a ‘timing code’ in which dynamics on the millisecond timescale is central to brain function, others instead argue that mean firing rates over more extended periods (a ‘rate code’) carry most of the relevant information. Existing tools, such as optogenetics, can be used to alter temporal structure of ne… Show more
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