2018
DOI: 10.1016/j.jcma.2017.07.012
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Microscopic entities, microorganisms that drastically affect human health need to be thoroughly investigated. A biofilm is an architectural colony of microorganisms, within a matrix of extracellular polymeric substance that they produce. Biofilm contains microbial cells adherent to one-another and to a static surface (living or non-living). Bacterial biofilms are usually pathogenic in nature and can cause nosocomial infections. The National Institutes of Health (NIH) revealed that among all microbial and chron… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3

Citation Types

4
635
0
29

Year Published

2019
2019
2022
2022

Publication Types

Select...
7
2

Relationship

0
9

Authors

Journals

citations
Cited by 1,020 publications
(668 citation statements)
references
References 41 publications
4
635
0
29
Order By: Relevance
“…Biofilms are initially formed when monolayers of planktonic bacteria attach irreversibly to a living or nonliving surface, followed by production of a three-dimensional extracellular matrix consisting mainly of exopolysaccharides (EPS). Maturation of the biofilm is followed by dispersion of bacteria, allowing further spread of infection (Jamal et al, 2018;Kostakioti, Hadjifrangiskou, & Hultgren, 2013). Biofilm forming ability is, therefore, considered as a virulence factor contributing to antibiotic resistance and the spread of nosocomial infections (Osland, Vestby, Fanuelsen, Slettemeås, & Sunde, 2012).…”
Section: Introductionmentioning
confidence: 99%
“…Biofilms are initially formed when monolayers of planktonic bacteria attach irreversibly to a living or nonliving surface, followed by production of a three-dimensional extracellular matrix consisting mainly of exopolysaccharides (EPS). Maturation of the biofilm is followed by dispersion of bacteria, allowing further spread of infection (Jamal et al, 2018;Kostakioti, Hadjifrangiskou, & Hultgren, 2013). Biofilm forming ability is, therefore, considered as a virulence factor contributing to antibiotic resistance and the spread of nosocomial infections (Osland, Vestby, Fanuelsen, Slettemeås, & Sunde, 2012).…”
Section: Introductionmentioning
confidence: 99%
“…They crosslink together and make protective layer in which bacteria lives with slow metabolic rate (Mann et al ; Alhede et al ; Yan et al . ; Jamal et al ). This protective barrier of biofilms offer strong resistance against antibiotics, host immune response, degrading enzymes etc (Stewart and Costerton ; Shahwany et al ).…”
Section: Introductionmentioning
confidence: 99%
“…Biofilms are mainly composed of~96-97% of water and extra polymeric substances (~3-4%) (EPS layer) which includes polysaccharides, proteins and nucleic acids (DNA and RNA). They crosslink together and make protective layer in which bacteria lives with slow metabolic rate (Mann et al 2009;Alhede et al 2011;Yan et al 2016;Jamal et al 2018). This protective barrier of biofilms offer strong resistance against antibiotics, host immune response, degrading enzymes etc (Stewart and Costerton 2001;Shahwany et al 2016).…”
Section: Introductionmentioning
confidence: 99%
“…The biofilm matures into a three‐dimensional structure that is difficult to penetrate or degrade in a process governed by bacterial quorum sensing (QS) via signalling molecules in accordance with population density (Miller and Bassler, ). Ultimately, the cell cluster is dispersed to release planktonic cells back into the environment to continue the cycle (Jamal et al ., ).…”
mentioning
confidence: 97%