Bacillus coagulans R11 consumption influenced the abundances of cecum antibiotic resistance genes in lead-exposed laying hens

Xing, Si-Cheng; Chen, Jingyuan; Cai, Yumeng; Huang, Chun-Bo; Liao, Xindi; Mi, Jiandui

doi:10.1016/j.envpol.2021.116562

Cited by 8 publications

(4 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It would be of significance to predict susceptible drugs for the monkeys' medication when they are sick. Tetracycline resistance gene was the most abundant gene reported in pigs [58,59], cattle [21], dogs [60] and chickens [61]. Also, some ARG such as MLS, MDR, and vancomycin were reported in underground waterways [62], rivers [63], and oceans [64].…”

Section: Arg Differences Between Wild and Captive Monkeysmentioning

confidence: 99%

Gut microbiome variations in Rhinopithecus roxellanae caused by changes in the environment

Zhao

Wang

et al. 2023

BMC Genomics

View full text Add to dashboard Cite

Background The snub-nosed monkey (Rhinopithecus roxellanae) is an endangered animal species mainly distributed in China and needs to be protected. Gut microbiome is an important determinant of animal health and population survival as it affects the adaptation of the animals to different foods and environments under kinetic changes of intrinsic and extrinsic factors. Therefore, this study aimed to elucidate gut fecal microbiome profiles of snub-nosed monkeys affected by several extrinsic and intrinsic factors, including raising patterns (captive vs. wild), age, sex, and diarrheal status to provide a reference for making protection strategies. Results The 16S rRNA gene sequencing was firstly used to pre-check clustering of 38 fecal samples from the monkeys including 30 wild and 8 captive (5 healthy and 3 diarrheal) from three Regions of Shennongjia Nature Reserve, Hubei Province, China. Then the 24 samples with high-quality DNA from 18 wild and 6 captive (4 healthy and 2 diarrheal) monkeys were subjected to shotgun metagenomic sequencing to characterize bacterial gut microbial communities. We discovered that the raising pattern (captive and wild) rather than age and sex was the predominant factor attributed to gut microbiome structure and proportionality. Wild monkeys had significantly higher bacterial diversity and lower Bacteroidetes/Firmicutes ratios than captive animals. Moreover, the gut microbiomes in wild healthy monkeys were enriched for the genes involved in fatty acid production, while in captive animals, genes were enriched for vitamin biosynthesis and metabolism and amino acid biosynthesis from carbohydrate intermediates. Additionally, a total of 37 antibiotic resistant genes (ARG) types were detected. Unlike the microbiome diversity, the captive monkeys have a higher diversity of ARG than the wild animals. Conclusion Taken together, we highlight the importance of self-reprogramed metabolism in the snub-nosed monkey gut microbiome to help captive and wild monkeys adapt to different intrinsic and extrinsic environmental change.

show abstract

Section: Arg Differences Between Wild and Captive Monkeysmentioning

confidence: 99%

Gut microbiome variations in Rhinopithecus roxellanae caused by changes in the environment

Zhao

Wang

et al. 2023

BMC Genomics

View full text Add to dashboard Cite

show abstract

“…However, tet M and tet W were significantly correlated with Bacteroidetes and Proteobacteria in swine manure, respectively ( Luo et al, 2021 ). Another study reported that feeding Bacillus coagulans R11 to laying hens exposed to lead obviously increased the abundances of aminoglycoside and chloramphenicol ARGs ( Xing et al, 2021 ).…”

Section: Discussionmentioning

confidence: 99%

New Estimation of Antibiotic Resistance Genes in Sediment Along the Haihe River and Bohai Bay in China: A Comparison Between Single and Successive DNA Extraction Methods

Zhang

et al. 2021

Front. Microbiol.

View full text Add to dashboard Cite

Sediment is thought to be a vital reservoir for antibiotic resistance genes (ARGs). Often, studies describing and comparing ARGs and their potential hosts in sediment are based on single DNA extractions. To date, however, no study has been conducted to assess the influence of DNA extraction efficiency on ARGs in sediment. To determine whether the abundance of ARGs is underestimated, we performed five successive extraction cycles with a widely used commercial kit in 10 sediment samples collected from the Haihe River and Bohai Bay. Our results showed that accumulated DNA yields after five extractions were 1.8–3.1 times higher than that by single DNA extractions. High-throughput sequencing showed that insufficient DNA extraction could generate PCR bias and skew community structure characterization in sediment. The relative abundances of some pathogenic bacteria, such as Enterobacteriales, Lactobacillales, and Streptomycetales, were significantly different between single and successive DNA extraction samples. In addition, real-time fluorescent quantitative PCR (qPCR) showed that ARGs, intI1, and 16S rRNA gene abundance strongly increased with increasing extraction cycles. Among the measured ARGs, sulfonamide resistance genes and multidrug resistance genes were dominant subtypes in the study region. Nevertheless, different subtypes of ARGs did not respond equally to the additional extraction cycles; some continued to have linear growth trends, and some tended to level off. Additionally, more correlations between ARGs and bacterial communities were observed in the successive DNA extraction samples than in the single DNA extraction samples. It is suggested that 3–4 additional extraction cycles are required in future studies when extracting DNA from sediment samples. Taken together, our results highlight that performing successive DNA extractions on sediment samples optimizes the extractable DNA yield and can lead to a better picture of the abundance of ARGs and their potential hosts in sediments.

show abstract

“…(Jafarpour et al 2017) Similarly, XL Chang et al confirmed the results by adding Bacillus coagulans SCC-19 to the feed at 1.0 × 10 8 CFU/g, and after 60 days of continuous feeding, carp reared in water with 0.5 mg/L of cadmium increased their body weight significantly, accumulated significantly less cadmium in the liver and kidneys than the control group, and had reduced symptoms of cadmium toxicity (Chang et al 2021). In addition, many studies have shown that Bacillus coagulans R11 has excellent lead ion adsorption capacity (Xing et al 2018(Xing et al , 2021. Iranian scholars have confirmed through a rat model that oral administration of Bacillus coagulans significantly prevented mercury toxicity, physiological indices such as creatinine and urea in rats were significantly diminished and oxidative stress was effectively alleviated (Majlesi et al 2017).…”

Section: Removal Of Heavy Metal Ions From Animalsmentioning

confidence: 98%

Application of Weizmannia coagulans in the medical and livestock industry

Wang

et al. 2022

Ann Microbiol

View full text Add to dashboard Cite

Purpose Products enriched with probiotics have always been fashionable. Weizmannia coagulans has become a hot research topic in the academic community due to their multiple functional properties and high resistance to stress, which can retain their activity in a variety of harsh environments. This review aims to evaluate the probiotic effects of different strains of Weizmannia coagulans in animals and humans and to inspire better exploitation of the value of this strain. Methods This review summarizes the latest research progress of Weizmannia coagulans from two major applications in animal breeding and human health. Results The functional properties of Weizmannia coagulans are extensively recognized. In animals, the strain can promote nutrient absorption, reduce mortality, and enhance the slaughter rate in livestock and poultry. In humans, the strain can be used to treat gastrointestinal disorders, immunomodulation, depressive symptoms, and non-alcoholic fatty liver. Weizmannia coagulans is projected as an ideal substitute for antibiotics and other chemical drugs. Conclusion Despite the outstanding functional properties of Weizmannia coagulans, there are numerous strains of Weizmannia coagulans and significant differences between strains in functional and physiological properties. Currently, there are few literature reports on the probiotic mechanism and functional gene identification of Weizmannia coagulans, which is crucial for the commercialization of Weizmannia coagulans and the benefit of human society.

show abstract

Bacillus coagulans R11 consumption influenced the abundances of cecum antibiotic resistance genes in lead-exposed laying hens

Cited by 8 publications

References 39 publications

Gut microbiome variations in Rhinopithecus roxellanae caused by changes in the environment

Gut microbiome variations in Rhinopithecus roxellanae caused by changes in the environment

New Estimation of Antibiotic Resistance Genes in Sediment Along the Haihe River and Bohai Bay in China: A Comparison Between Single and Successive DNA Extraction Methods

Application of Weizmannia coagulans in the medical and livestock industry

Contact Info

Product

Resources

About