Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis

Management of Crohn Disease

“…If this combination treatment option is used, patients should be carefully monitored for bone marrow suppression. Furthermore, thiopurines, such as azathioprine and mercaptopurine, are well-established maintenance treatments for IBD, which cost approximately €1 to €3 ($1.19-$3.58) per day …”

Management of Crohn Disease

“…If this combination treatment option is used, patients should be carefully monitored for bone marrow suppression. Furthermore, thiopurines, such as azathioprine and mercaptopurine, are well-established maintenance treatments for IBD, which cost approximately €1 to €3 ($1.19-$3.58) per day …”

Clinical Features of Interleukin 10 Receptor Gene Mutations in Children With Very Early–Onset Inflammatory Bowel Disease

“…Therefore, azathioprine was also used to treat these 3 patients. Considering the mechanism of action of azathioprine, this drug is not expected to be greatly effective for the treatment of patients with IL10 receptor mutations, resulting in dysfunction in the genetic pathway (30). In line with these considerations, the response to azathioprine þ steroids treatment in our 3 patients was insufficient.…”

Management of ulcerative colitis in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease updated in 2023

“…Thiopurines, such as azathioprine (AZA) and 6-mercaptopurine (6-MP), are immunomodulators that effectively maintain remission in patients who do not respond to or depend on corticosteroids. Moreover, they can be considered for patients who fail or cannot tolerate mesalamine or sulfasalazine [ 118 ].…”

Management of Crohn Disease

“…If this combination treatment option is used, patients should be carefully monitored for bone marrow suppression. Furthermore, thiopurines, such as azathioprine and mercaptopurine, are well-established maintenance treatments for IBD, which cost approximately €1 to €3 ($1.19-$3.58) per day …”

Clinical Features of Interleukin 10 Receptor Gene Mutations in Children With Very Early–Onset Inflammatory Bowel Disease

“…Therefore, azathioprine was also used to treat these 3 patients. Considering the mechanism of action of azathioprine, this drug is not expected to be greatly effective for the treatment of patients with IL10 receptor mutations, resulting in dysfunction in the genetic pathway (30). In line with these considerations, the response to azathioprine þ steroids treatment in our 3 patients was insufficient.…”

Management of ulcerative colitis in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease updated in 2023

“…Thiopurines, such as azathioprine (AZA) and 6-mercaptopurine (6-MP), are immunomodulators that effectively maintain remission in patients who do not respond to or depend on corticosteroids. Moreover, they can be considered for patients who fail or cannot tolerate mesalamine or sulfasalazine [ 118 ].…”

Management of Crohn Disease

“…If this combination treatment option is used, patients should be carefully monitored for bone marrow suppression. Furthermore, thiopurines, such as azathioprine and mercaptopurine, are well-established maintenance treatments for IBD, which cost approximately €1 to €3 ($1.19-$3.58) per day …”

Clinical Features of Interleukin 10 Receptor Gene Mutations in Children With Very Early–Onset Inflammatory Bowel Disease

“…Therefore, azathioprine was also used to treat these 3 patients. Considering the mechanism of action of azathioprine, this drug is not expected to be greatly effective for the treatment of patients with IL10 receptor mutations, resulting in dysfunction in the genetic pathway (30). In line with these considerations, the response to azathioprine þ steroids treatment in our 3 patients was insufficient.…”

Management of ulcerative colitis in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease updated in 2023

“…Thiopurines, such as azathioprine (AZA) and 6-mercaptopurine (6-MP), are immunomodulators that effectively maintain remission in patients who do not respond to or depend on corticosteroids. Moreover, they can be considered for patients who fail or cannot tolerate mesalamine or sulfasalazine [ 118 ].…”