Axillary staging using ultrasound-guided fine needle aspiration biopsy in locally advanced breast cancer

Oruwari, Jovita U. N.; Chung, Maureen A.; Koelliker, Susan; Steinhoff, Margaret M.; Cady, Blake

doi:10.1016/s0002-9610(02)00957-1

Cited by 82 publications

(40 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[52][53][54][55][56] Patients who are negative for lymph node metastasis in the initial staging process may be candidates for SLN biopsy, and patients with documented metastasis may be candidates for complete dissection of axillary lymph nodes after the completion of chemotherapy. Figure 4 illustrates the utility of US-guided FNA of axillary lymph nodes in the initial staging of a patient with advanced breast cancer.…”

Section: Fna Of Lymph Nodes In Breast Cancer/krishnamurthymentioning

confidence: 99%

Current applications and future prospects of fine‐needle aspiration biopsy of locoregional lymph nodes in the management of breast cancer

Krishnamurthy

2009

Cancer Cytopathology

View full text Add to dashboard Cite

Staging of disease is routine in the evaluation of patients newly diagnosed with breast cancer. Assessment of palpable and/or nonpalpable locoregional lymph nodes is an important component of the initial staging.Ultrasound (US) is the favored imaging modality for the initial investigation of lymph nodes and results in a significant increase in the specificity of the overall evaluation when used in conjunction with fine-needle aspiration (FNA). This review provides a concise summary, based on published literature, of the current applications and future prospects of FNA biopsy of locoregional lymph nodes in the initial staging and subsequent surgical management of patients with breast cancer. Patients undergo either sentinel lymph node (SLN) biopsy or complete axillary lymph node dissection, based on whether the axillary lymph node status is determined to be negative or positive in the initial staging process. The status of lymph nodes in the supraclavicular, infraclavicular, and internal mammary regions provides more accurate staging information and also impacts subsequent surgical management. The identification and evaluation of intramammary lymph nodes can add value in the overall assessment of patients with breast cancer. The feasibility of noninvasive imaging modalities for SLN mapping in animal models has indicated a good potential for FNA biopsy in the subsequent investigation of SLNs identified noninvasively in humans. Staging of the malignant tumor is a routine component in the assessment of patients who are newly diagnosed with breast cancer. Breast cancer staging aids in the appropriate management of patients at each stage of disease and is useful in estimating the prognosis for a patient at a particular stage. The routine staging process includes taking a thorough history of the patient, physical examination, mammography, ultrasonography (US) of the breast and lymph node basins, computed tomography (CT) scan of the abdomen, bone scanning, and chest radiography. Cancer is assigned a clinical stage at the time of the initial diagnosis based on the findings of the physical examination, radiologic studies, and core needle biopsy (CNB) of the

show abstract

Section: Fna Of Lymph Nodes In Breast Cancer/krishnamurthymentioning

confidence: 99%

Current applications and future prospects of fine‐needle aspiration biopsy of locoregional lymph nodes in the management of breast cancer

Krishnamurthy

2009

Cancer Cytopathology

View full text Add to dashboard Cite

show abstract

“…A probable reason for this discrepancy may be the small sample included in this study, in view of such a prevalent disease. In a study by Oruwari et al (22), the sample was similar, but included patients with more advanced disease. As a result, the sensitivity and specificity were higher.…”

Section: Discussionmentioning

confidence: 99%

“…By contrast, using US-guided FNA, certain authors have demonstrated a sensitivity and specificity ranging from 42. (20)(21)(22)(23)(24)(25)(26)(27)(28). US-guided FNA has a high accuracy rate (5,7).…”

Section: Introductionmentioning

confidence: 99%

Comparative study between ultrasound-guided fine needle aspiration cytology of axillary lymph nodes and sentinel lymph node histopathology in early-stage breast cancer

et al. 2017

View full text Add to dashboard Cite

Abstract. The replacement of sentinel lymph node biopsy (SNB) by ultrasound-guided fine-needle aspiration (US-guided FNA) cytology of axillary lymph nodes is controversial, despite the simplicity and reduced cost of the latter. In the present study, US-guided FNA was performed in 27 patients with early-stage breast cancer for comparison with SNB. Data were analyzed by calculation of sample proportions. Tumor subtypes included invasive ductal carcinoma (85%), invasive lobular carcinoma (7%), and tubular and metaplastic carcinoma (4%). FNA had a sensitivity of 45%, specificity of 100%, positive predictive value of 100% and a negative predictive value of 73%. Axillary lymph node cytology obtained by US guided-FNA in patients with breast cancer had a specificity similar to that of sentinel lymph node histopathology in the presence of axillary node metastases. However, when lymph node cytology is negative, it does not exclude the existence of metastatic implants, due to its low sensitivity in comparison to sentinel lymph node histopathology.

show abstract

“…10 Oruwari et al demonstrated that ultrasound of the axilla was more accurate in staging the axilla than preoperative clinical examination and found the sensitivity of USG was 91%, specificity 100% and accuaracy 92%. 11 Sapino et al recommended that preoperative evaluation of axilla by USG should be used because of low cost and high specificity. 12 He considered nodes suspicious when they had 2D enlargement imparting a rounded appearance, an echo-poor central hilus, and eccentricity of the nodal cortex.…”

Section: Discussionmentioning

confidence: 99%

Correlation of clinical examination and ultrasonogram with histopathology in predicting the metastatic axillary lymph nodes in breast cancer

2016

View full text Add to dashboard Cite

Axillary staging using ultrasound-guided fine needle aspiration biopsy in locally advanced breast cancer

Cited by 82 publications

References 6 publications

Current applications and future prospects of fine‐needle aspiration biopsy of locoregional lymph nodes in the management of breast cancer

Current applications and future prospects of fine‐needle aspiration biopsy of locoregional lymph nodes in the management of breast cancer

Comparative study between ultrasound-guided fine needle aspiration cytology of axillary lymph nodes and sentinel lymph node histopathology in early-stage breast cancer

Correlation of clinical examination and ultrasonogram with histopathology in predicting the metastatic axillary lymph nodes in breast cancer

Contact Info

Product

Resources

About