Axial sarcoidosis mimicking radiographic sacroiliitis

Binicier, Ömer Burçak; Sarı, İ̇smail; Sen, Gerçek; Önen, Fatoş; Akkoç, Nurullah; Manisalı, Metin; Akar, Servet

doi:10.1007/s00296-008-0677-6

Cited by 20 publications

(27 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As in other forms of sarcoidosis, a biopsy is required to establish the diagnosis of osseous lesions. It is not possible to distinguish granulomatous bone involvement from other causes by MRI or other imaging studies, making biopsy necessary for diagnosis [7][8][9][10][11].…”

Section: Granuloma Of Sarcoidosis In the Bonementioning

confidence: 98%

Osseous sarcoidosis: a case series

et al. 2014

View full text Add to dashboard Cite

Sarcoidosis is an inflammatory disorder characterized by noncaseating granulomas infiltrating affected organs. Any organ system can be involved, and more than 90 % of patients have a primary pulmonary manifestation. The incidence of radiographically evident bone involvement has been reported over a wide range: from 3 to 39 % depending on the population studied and imaging modalities used. Any bone may be affected in osseous sarcoidosis. Bilateral involvement of the phalanges of the hand and feet is most common. However, reports of long bone, skull, rib and vertebral involvement have appeared. To date, there are no specific tools for the assessment of skeletal disease activity in sarcoidosis. Plain radiograph picks lesions in the small bones of hands and feet greater than does in other bones. Bone scan is useful for defining the extent of the skeletal disease and bone marrow involvement. Magnetic resonance imaging usually demonstrates multifocal lesions within the vertebrae that are hypointense on T1-weighted images and hyperintense on T2-weighted images. In cases of multifocal bone lesions and an established diagnosis of sarcoidosis, a diagnosis of bone sarcoidosis should be considered in the differential diagnosis. Optimal treatment of osseous sarcoidosis remains controversial. We present five cases of multisystem sarcoidosis with skeletal involvement including long bones and vertebrae and a description of immunosuppressive therapies used in our patients. A literature review highlighting the diagnostic approach using radiographic imaging, as well as treatment strategies, is provided.

show abstract

Section: Granuloma Of Sarcoidosis In the Bonementioning

confidence: 98%

Osseous sarcoidosis: a case series

et al. 2014

View full text Add to dashboard Cite

show abstract

“…[8] Radyolojik olarak üst dorsal, alt lomber ve servikal vertebralarda litik, sklerotik veya miks lezyonlar görülebilir. [23] ‹ntervertebral disk aral›klar› genellikle korunur. [24] Ay›r›c› tan›da spondilartritler, lenfoma, myelom, tüberküloz ve metastatik kanserler akla gelmelidir ve kesin tan› için biyopsi gerekebilir.…”

Section: Kemik Tutulumuunclassified

Romatolog gözüyle sarkoidoz

Tarhan¹

2013

RAED Derg

View full text Add to dashboard Cite

“…In several cases, treatment with prednisolone has led to symptom remission and to objective remission of the condition's affects [4][5][6], whilst other cases have been noted where there has been no treatment and no evidence of progression [7]. Successful treatment of vertebral sarcoidosis with methotrexate has also been previously reported [8]; in general though, treatment of bone sarcoidosis is disappointing [9].…”

Section: Positron Emission Tomography Withmentioning

confidence: 99%